학력

1990 – 1994. 고려대학교 농학사
1994 – 1996. 고려대학교 농학석사
1996 – 2003. 고려대학교 농학박사

논문

[국제 전문 학술지]
● Potential effect of defatted mealworm hydrolysate on muscle protein synthesis in C2C12 cells and rats. 2024. applied sciences.
● Protective effects on neuronal SH-SY5Y cells and antioxidant activity enzymatic hydrolyzate from silkworms fed the leaves of Cudrania tricuspidata. 2024. applied sciences.
● Effects of hydrolysates from silkworms fed Cudrania tricuspidata leaves on improvement of memory in rats with impaired memory induced by scopolamine. 2023. applied sciences.
● Correlation of attention deficit hyperactivity disorder with gut microbiota according to the dietary intake of Korean elementary school students. 2022. PLOS ONE.
● Lifestyle intervention program reduces metabolic syndrome in a high-risk population. 2022. Toxicology and Environmental Health Sciences.
● Butyrate modulates mucin secretion and bacterial adherence in LoVo cells via MAPK signaling. 2022. PLOS ONE.
● Imbalanced dietary intake alters the colonic microbial profile in growing rats. 2021. PLOS ONE.
● Effect of Triticum turgidum ssp. turanicum on serum lipid levels and colonic microbiota of dyslipidemia-induced rats. 2021. Toxicology and Environmental Health Sciences.
● Development of livestock feed additives using porcine blood cells. 2021. Journal of Animal Physiology and Animal Nutrition.
● Enzymatic hydrolysis of egg white protein exerts a hypotensive effect in spontaneously hypertensive rats. 2019. Food Science of Animal Resources. 39, 980-987.
● Manufacture and physicochemical properties of chitosan oligosaccharide/A2 beta-casein nano-delivery system entrapped with resveratrol. 2019. Food Science of Animal Resources. 39, 831-843.
● Impact of oral immunoglobulins on animal health-A review. 2019. Animal Science Journal. 90, 1099-1110.
● Hypoallergenic and physicochemical properties of the A2 beta-casein fraction of goat milk. 2017. Korean Journal for Food Science of Animal Resources. 37, 941-948
● Purification and anti-pathogenic properties of immunoglobulin concentrates from porcine blood. 2017. Korean Journal for Food Science of Animal Resources. 37, 757-765.
● Evaluation of the digestibility of Korean Hanwoo beef cuts using the in vitro physicochemical upper gastrointestinal system. 2017. Korean Journal for Food Science of Animal Resources. 37, 687-694.
● Hydrolysis by Alcalase Improves Hypoallergenic Properties of Goat Milk Protein. 2016. Korean Journal for Food Science of Animal Resources. 36, 516-522.
● Physicochemical Characterization and Potential Prebiotic Effect of Whey Protein Isolate/Inulin Nano complex. 2016. Korean Journal for Food Science of Animal Resources. 36, 267-274.
● In Vitro Effects of Dietary Inulin on Human Fecal Microbiota and Butyrate Production. 2015. Journal of Microbiology and Biotechnology. 25(9), 1555-1558.
● Butyrate modulates bacterial adherence on LS174T human colorectal cells by stimulating mucin secretion and MAPK siganling pathway. 2015. Nutrition Research and Practice. 9(4), 343-349.
● Korean ginseng modulates the ileal microbiota and mucin gene expression in the growing rat. 2014. Food and Function. 5, 1506-1512.
● Orally administered ovine serum immunoglobulins modulate the intestinal levels of lactobacillus and enterobacteria in the growing rat. 2013. Journal of Animal Science. 91, 3724-3732.
● Recovery of intact IgG in the gastrointestinal tract of the growing rat following ingestion of an ovine serum immunoglobulin. 2013. Journal of Animal Physiology and Animal Nutrition. 98(2), 209-214.
● Green and gold kiwifruit peel ethanol extracts potentiate pentobarbital-induced sleep in mice via a GABAergic mechanism. 2013. Food Chemistry. 136, 160-163.
● Comparative analysis of RNA silencing suppression activities between viral suppressors and an endogenous plant RNA-dependent RNA polymerase. 2012. Virus Genes. 44, 495-504.
● Dietary supplementation with ovine serum immunoglobulin is associated with increased gut mucin secretion in the growing rat. 2011. Animal. 5, 1916-1922.
● Indian culinary plants enhance glucose-induced insulin secretion and glucose consumption in INS-1 b-cells and 3T3-L1 adipocytes. 2011. Food Chemistry. 129, 1120-1125.
● Dietary supplementation with ovine serum immunoglobulin attenuates acute effects on growth, organ weights, gut morphology and intestinal mucin production in the growing rat challenged with Salmonella enteritidis. 2011. Animal. 5, 1570-1578.
● Ovine serum immunoglobulin has immunomodulatory effects in growing rats gavaged with Salmonella enteritidis. 2011. Journal of Nutrition. 141, 950-956.
● Green kiwifruit modulates the colonic microbiota in growing pigs. 2011. Letters in Applied Microbiology. 52, 379-385.
● Microencapsulation of probiotic bacteria using pH-induced gelation of sodium caseinate and gellan gum. 2011. International Dairy Journal. 21, 247-253.
● Reproductive and metabolic endorcrinology of Romney rams selected for high or low circulating IGF-I concentrations. 2010. Small Ruminant Research. 93, 186-192.
● Immunomodulatory effects of ovine serum immunoglobulin in the growing rat. 2010. Animal. 4, 1702-1708.
● Rams genetically superior for IGF-1 do not exhibit improved male reproductive traits. 2009. Animal Reproduction Science. 118, 223-230.
● The in vitro anti-pathogenic activity of immunoglobulin concentrates extracted from ovine blood. 2009. Applied Biochemisty and Biotechnology. 157, 442-452.
● Anticancer activity of lactoferrin isolated from caprine colostrum on human cancer cell lines. 2009. International Journal of Dairy Technology. 62, 277-281.
● Orally administered ovine serum immunoglobulins influence growth performance, organ weights and gut morphology in growing rats. 2009. Journal of Nutrition. 139, 244-249.
● Hydrolysed casein influences intestinal mucin gene expression in the rat. 2008. Journal of Agricultural and Food Chemistry. 56, 5572-5576.
● Characterization and purification of acidocin 1B, a bacteriocin produced by Lactobacillus acidophilus GP1B. 2007. Journal of Microbiology and Biotechnology. 17, 774-783.
● Microencapsulation of Lactobacillus acidophilus ATCC 43121 with prebiotic substrates using a hybridization system. 2007. International Journal of Food Science and Technology. 42, 411-419.
● Food-derived bioactive peptides influence gut function. 2007. International Journal of Sport Nutrition and Exercise Metabolism. 17, S5-S22 (Suppl).
● Changes in the levels of insulin-like growth factors (IGF-I and IGF-II) in bovine milk according to the lactation period and parity. 2007. Asian-Aust. J. Anim. Sci. 20, 119-123.
● Inhibitory effects of Lactobacillus acidophilus lysates on the cytotoxic activity of shiga-like toxin 2 produced from Escherichia coli O157:H7. 2006. Letters in Applied Microbiology. 43, 502-507.
● Effects of Lactobacillus strains on cancer cell proliferation and oxidative stress in vitro. 2006. Letters in Applied Microbiology. 42, 452-458.
● Function of cell-bound and released exopolysaccharides produced by Lactobacillus rhamnosus ATCC 9595. 2006. Journal of Microbiology and Biotechnology. 16, 939-945.
● Rapid identification of Lactobacillus acidophilus by restriction analysis of the 16S-23S rRNA intergenic spacer region and flanking 23S rRNA gene. 2005. Biotechnology Letters. 27, 1183-1188.
● Optimization of technical conditions for the transformation of Lactobacillus acidophilus strains by electroporation. 2005. Journal of Applied Microbiology. 99, 167-174.
● Functionality and physico-chemical characteristics of bovine and caprine mozzarella cheeses during refrigerated storage. 2003. Journal of Dairy Science. 86, 2790-2798.
● Bacteriocin Produced by Lactobacillus acidophilus ATCC 4356: Characterization and Purification. 2002. Food Sci. Biotechnol. 11(5), 531-536.
● New response surface approach to optimize medium composition for production of bacteriocin by Lactobacillus acidophilus ATCC 4356. 2002. Journal of Microbiology and Biotechnology. 12, 449-456.


[국내 전문 학술지]
● Functional properties of hydrolysate from silkworms fed Cudrania tricuspidata. 2022. Korean Journal of Food Science and Technology. 54, 88-93.
● A study on the physicochemical properties of sausage analogue made with mixed bean protein concentrate. 2020. Korean Journal of Food Science and Technology. 52, 641-648.
● Studies on the characteristics of concentrated soy protein. 2020. Korean Journal of Food Science and Technology. 52, 459-466.
● The relationship of metabolic syndrome with dairy intake and physical activity in Korean adults: from the Korean national health and nutrition examination surveys, 2016-2017. 2020. Journal of the Korea Convergence Society. 11, 109-118.
● Estimation of digestibility of Hanwoo cuts using in vitro physicochemical gastroduodenal system. 2018. Journal of the Korean Society of Food Science and Nutrition. 47, 1029-1035.
● Enhancement of viability of Weissella cibaria CMU by low-temperature encapsulation. 2018. Journal of Milk Science and Biotechnology. 36, 171-177.
● Flavonoid in clover honey exerts a hypnotic effect via positive allosteric modulation of the GABAA-BZD receptor in mice. 2017. The Korean Journal of Food and Nutrition. 30, 1364-1369.
● Development and characterization of a hydrolyzed goat milk protien/chitosan oligosaccharide nano-delivery system. 2017. Journal of Milk Science and Biotechnology. 35, 208-214.
● The commercial value of goat milk in food industry. 2016. Korean J. Dairy Sci. Technol. 34, 173-180.
● Development of a Novel PCR Primer for Detection of Staphylococcus aureus. 2015. Journal of Agriculture and Life Sciences. 49(1), 147-153.
● Transient expression of homologous hairpin RNA interferes with Cucumber mosaic virus infection in Nicotiana benthamiana. 2014. The Journal of the Korean Society of international Agriculture. 26(21), 1-9.
● Adulteration of caprine milk products by bovine milk in Korea. 2013. Korean J. Dairy Sci. Technol. 31, 127-131.
● Nutritional value and characterization of Jersey Milk. 2013. Journal of Agriculture &Life Science. 47, 111-121.
● Use of Bacteriocin Produced by Lactococcus sp. CU216 with pH Sensitive Liposome Entrapment. 2004. Korean J. Food Sci. Ani. Resour. 24(1), 97-102.
● Adhesion Ability and Inhibition of Lactobacillus acidophilus on Adhesion of Enterohemorrhagic E. coli O157:H7 to Intestinal Epithelial Cells. 2004. Korean J. Food Sci. Ani. Resour. 24(1), 86-91.
● Purification, Bacteriolytic Action and Plasmid Isolation of Acidocin 4A Produced by Lactobacillus acidophilus GP4A. 2003. J. Korean Dairy Technol. Sci. 21(2), 114-119.
● Formation of Cheese Flavor and EMC Technology. 2003. J. Korean Dairy Technol. Sci. 21(2), 88-96.
● Dry Enteric Coating Process of Lactic Acid Bacteria by Hybridization System. 2002. Korean J. Food Sci. Technol. 34(5), 856-861.
● Antimicrobial Effects of a Bacteriocin Mixture from Lactic Acid Bacteria against Foodborne Pathogens. 2002. Korean J. Food Sci. Ani. Resour. 22(2), 164-171.
● Development of Bacteriocin Preparation from Lactic Acid Bacteria against Salmonella Using an Experimental Design for Mixtures. 2002. J. Korean Dairy Technol. Sci. 20(1), 1-8.
● Characterization and Inhibitory Activity on Staphylococcus aureus of a Bacteriocin Produced by Lactobacillus plantarum KU107. 2002. Korean J. Food Ani. Resour. 22(1), 81-86.
● Estimation of Insulin Like Growth Factor-I (IGF-I) Concentration in Raw Milk and Milk Whey by Various Milk Heat Treatment. 2001. J. Korean. Dairy Technol. Sci. 19(2), 98-102.
● A Study on the Dairy Information System and Effective Dairy Extension Service System. 2001. J. Korean. Dairy Technol. Sci. 19(1), 22-29.
● Fractionation and Physicochemical Characteristics of Caprine Casein by DEAE-Cellulose. 2000. J. Korean. Dairy Technol. Sci. 18(1), 1-8.
● Characteristics and Purification of Bacteriocin Produced by Lactobacillus acidophilus GP4A. 1999. J. Korean. Dairy Technol. Sci. 17(1), 1-10.
● Electrophoretic Analysis of Heated Milk Fat Globule Membrane Protein. 1997. Korean J. Food Sci. Ani. Resour. 17(3), 240-245.
● Molecular Composition and Fractionation of Colostral Casein with Advancing Lactation. 1997. Korean

경력

2003 – 2004 고려대학교 식품과학부 박사후연구원
2004 – 2005 고려대학교 생명자원연구소 선임연구원
2006 – 2010 New Zealand, Massey University, Postdoctoral Fellow
2010 – 2011 New Zealand, Massey University, Research Officer (전임 연구교수)
2009 – 2011 New Zealand Delegation for Focal Point Project (Food Innovation) with Korean Scientists
2009 – 현 재 The New Zealand Institute of Food Science and Technology 정회원
2011 – 2017 삼육대학교 동물생명자원학과 부교수
2012 – 현 재 삼육대학교 부설 바이오소재 연구소 소장
2012 – 현 재 International Dairy Federation-Korea 분과위원
2012 – 2019 (사)한국유가공학회 학술간사, 학술위원장, 편집위원장
2014 – 2019 (사)한국축산식품학회 학술간사, 기획간사, 산업지 편집간사, 영문지 편집위원
2016 – 2018 (사)한국식품영양과학회 PNF 편집위원
2017 – 2019 삼육대학교 대학원 식품생명산업학과 학과장
2018 - 현 재 삼육대학교 식품영양학과/바이오융합공학과 교수
2018 – 2019 삼육대학교 연구산학처 부처장/산학협력단 부단장
2020 - 2023 삼육대학교 연구산학처 처장/산학협력단 단장
2023 - 현 재 : 구리시 어린이사회복지급식관리지원센터 센터장
2025 - 현 재 (사)한국축산식품학회 기획위원장
2025 - 현 재 (사)한국낙농식품응용생물학회 부회장

[주요 연구분야]
● 동물 실험 모델 및 인체 실험을 활용한 기능성 소재의 장 미생물군집, 면역 및 뇌 건강에 미치는 영향 연구
● 식품, 화장품 및 동물사료에 적용 가능한 기능성 소재 개발 연구
● 다양한 생체 내외 실험 기법을 이용한 소재의 기능성 검증 및 기작 연구
● Probiotics의 선발, 특성 규명 및 캡슐화 연구
● 인체 소화기관 생체외 모델을 이용한 다양한 식품의 소화율 평가 연구
● 식물성 대체육 생산 및 가공기술 개발

학력

(B.S) 2011-2017 Sahmyook University, College of Pharmacy, Pre-med-science
(Ph.D) 2017-2024 Seoul National University College of Medicine (Translational Medicine, Toxicology)

논문

JI Kim, MY Park, E Kwon, T Mashimo, HJ Kang, BC Kang. Validation of a B cell acute lymphoblastic leukemia xenograft rat model for integrated efficacy, pharmacokinetics and safety of CD19 CAR-T. Toxicological Research(2026), 1-12

JH Ahn, NY Lee, HJ Bae, JI Kim, J Kwak, E Kwon, G Roh, S Bae, SY Lee, IK Hwang, J Lee, HJ Park, SP Kwon, EK Bang, JE Kim, G Keum, JH Nam, BC Kang. Nonclinical Safety Evaluation Strategies for mRNA/LNPs Platform Agents: Evidence from Comprehensive Animal Toxicity Studies. Toxicology Letters (2026), 111941

JH Ahn, JH Kim, J Kwak, JI Kim, NY Lee, HJ Choi, HJ Bae, SH Cho, SG Jung, HM Kwon, E Kwon, DH Kim, MJ Kim, DS Yoon, SH Kim, BT Kim, BC Kang. JAK–STAT inhibitory effect of IN‐115314, a novel small molecule inhibitor, and pharmacokinetic/pharmacodynamic study in canine. British Journal of Pharmacology (2025),182:5071–5082

Jl Kim, HJ Lim, E Kwon, T Mashimo, BC Kang. Immune deficiency phenotypes of Il2rg, Rag2or Il2rg/Rag2double knockout rats; establishment of human leukemia xenograft models. Laboratory Animal Research (2024),40 (43)

JI Kim,MY Park, E Kwon, HJ Kang, BC Kang. CD19 chimeric antigen receptor T cell therapy in leukemia xenograft mouse: Anti-leukemic efficacy, kinetics, and 4-week single-dose toxicity.
Toxicology and Applied Pharmacology(2023), 475, 116628

J Kim, M Park, G Baek, JI Kim, E Kwon, BC Kang, JI Kim, HJ Kang. Tagmentation-based analysis reveals the clonal behavior of CAR-T cells in association with lentivector integration sites. Molecular Therapy-Oncolytics (2023), 30, 1-13

JM Kim, J Kwak, HJ Lim, JI Kim, BC Kang. Diagnosis and treatment of macrocytic anemia in a perinatal common marmoset: a case report.Laboratory animal research(2022), 38(1), 6

JM Kim, J Kwak, JI Kim, D Kim, BC Kang. Diagnosis of thrombotic microangiopathy in preeclampsia in the common marmoset (Callithrix jacchus) and treatment by cesarean sectionJournal of Medical Primatology(2022), 51 (3), 195-198

J Kwak, JM Kim, CG Woo, JI Kim, SK Ryu, BC Kang. Acute aspiration pneumonia in common marmoset (Callithrix jacchus) with marmoset duodenal dilation syndrome: A case report. Journal of Medical Primatology(2022), 51 (4), 253-255

JS Park, JI Kim, HJ Lim, SK Ryu, E Kwon, KM Han, KT Nam, HW Lee, BC Kang. Differential manifestation of ocular phenotypes in TALEN-mediated p19arf knockout FVB/N and C57BL/6J mouse lines. Genes & genomics (2020), 42, 1023-1033

JI Kim, JS Park, H Kim, SK Ryu, J Kwak, E Kwon, JW Yun, KT Nam, HW Lee, BC Kang. CRISPR/Cas9-mediated knockout of CD47 causes hemolytic anemia with splenomegaly in C57BL/6 mice.Laboratory animal research(2018), 34, 302-310

JI Kim, JS Park, H Kim, SK Ryu, J Kwak, E Kwon, JW Yun, KT Nam, HW Lee, BC Kang. CRISPR/Cas9-mediated knockout of Rag-2 causes systemic lymphopenia with hypoplastic lymphoid organs in FVB mice.Laboratory animal research(2018), 34, 166-175

HJ Lee, JI Kim, JS Park, J Roh, J Lee, BC Kang, HW Lee. CRISPR/Cas9-mediated generation of a Plac8 knockout mouse model. Laboratory animal research(2018), 34, 279-287

경력

(Post-doc Researcher) 2024-2026 Seoul National University Hospital. Biomedical Research Institute, Department of Experimental Animal Resources

논문

[국제 전문 학술지]

Correlation of attention deficit hyperactivity disorder with gut microbiota according to the dietary intake of Korean elementary school. 2022. PLoS One. https://doi.org/10.1371/journal.pone.0275520

Butyrate modulates mucin secretion and bacterial adherence in LoVo cells via MAPK signaling. 2022. PLoS One. https://doi.org/10.1371/journal.pone.0269872

Imbalanced dietary intake alters the colonic microbial profile in growing rats. 2021. PLoS One. https://doi.org/10.1371/journal.pone.0253959

Development of livestock feed additives using porcine blood cells. 2021. Journal of Animal Physiology and Animal Nutrition. https://doi.org/10.1111/jpn.13498

Enzymatic Hydrolysis of Egg White Protein Exerts a Hypotensive Effect in Spontaneously Hypertensive Rats. 2019. Korean Society for Food Science of Animal Resources. 39, 980-987.

Hypoallergenic and physicochemical properties of the A2 b-casein fraction of goat milk. 2017. Korean Society for Food Science of Animal Resources. 37, 941-948.

Evaluation of the digestibility of korean hanwoo beef cuts using the in vitro physicochemical upper gastrointestinal system. 2017. Korean Society for Food Science of Animal Resources. 37, 682-689.

Purification and anti-pathogenic properties of immunoglobulin concentrates from porcine blood. 2017. Korean Society for Food Science of Animal Resources. 37, 743-751.

Hydrolysis by alcalase improves hypoallergenic properties of goat milk protein. 2016. Korean Society for Food Science of Animal Resources. 34, 516-522.

In vitro effects of dietary inulin on human fecal microbiota and butyrate production. 2015. Journal of Microbiology and Biotechnology. 25, 1555-1558.

Butyrate modulates bacterial adherence on LS174T human colorectal cells by stimulating mucin secretion and MAPK signaling pathway. 2015. Nutrition Research and Practice. 9, 343-349.


[국내 전문 학술지]
Analysis of nutrients and antioxidants of sterilized and non-heat-pressed perilla oil. 2022. Korean journal of food science and technology. 54, 264-271.

The nutritional functions and physiological activities of rose hip (Rosa canina fruits): A systematic review. 2022. Korean journal of food science and technology. 54, 369-376.

A Study on the Relationship between Dietary Patterns and the Subjective Stress Perception of Korean Adult Men: Based on the Korea National Health and Nutrition Examination Survey, 2014~2016. 2022. Journal of the Korean dietetic association. 28, 85-98.

Studies on the general analysis and antioxidant component analysis of Chenopodium album var. centrorubrum and biochemical analysis of blood of mice administered C. album. 2019. Korean journal of food science and technology. 51, 492-498.

Estimation of Digestibility of Hanwoo Cuts Using In Vitro Physicochemical Gastroduodenal System. 2018. Journal of the Korean Society of Food Science and Nutrition. 47, 1029-1035.

Comparison of Components and Antioxidant Activity of Cherry, Aronia, and Maquiberry. 2018. The Korean journal of food and nutrition. 31, 729-736.

Enhancement of Viability of Weissella cibaria CMU by Low-Temperature Encapsulation. 2018. Journal of milk science and biotechnology. 171-177.

Analysis of the General Components of Acorns and Effects of Acorn Extracts and High-Fat Diet Supplements on the Blood Lipid Factor and Cytokine Levels in Mice. 2017. The Korean journal of food and nutrition. 30, 148-155.

The Commercial Value of Goat Milk in Food Industry. 2016. Journal of milk science and biotechnology. 34, 173-180.

Effects of Pyroligneous Liquor on Olive, Flaxseed and Perilla Oils in Lipid Metabolism of Mice. 2013. The Korean journal of food and nutrition. 26, 242-248.

A Study on the Differences in the Dietary Habits, Nutrient Intake and Health Status of Vegetarian (Lacto-Ovo Vegetarian) and Non-Vegetarian Korean Elementary School Children. 2011. Journal of the Korean Society of Food Science and Nutrition. 40, 416-425.

Study on the Dietary Habit, Nutrient Intake, and Health Status According to Their Majors Among College Women in Sahmyook University. 2010. Journal of the Korean Society of Food Science and Nutrition. 39, 826-836.