학력

삼육대학교 약학과 졸업
경희대학교 대학원 약학대학 석사 졸업
경희대학교 대학원 약학대학 박사 졸업

논문

Controlled releas of silymarin from chitosan carrier, 한국 약제학회지, 1995. 3 호병균, 서성훈, 강진양

Controlled releas of piracetam with ion exchange resin, 한국 약제학회지, 1995. 6 강진양, 서성훈, 이경태

Development of stable magnesium citrate carthartic,한국 약제학회지, 1995. 10 이종석, 서성훈, 강진양

알긴산 비드를 이용한 하제의 연구,생명과학지(삼육대논문집), 3권, 1997. 3 강진양

Poly(D, L - lactic) acid를 이용한 Piracetam의 Microsphere 제조, 생명과학지(삼육대논문집), 4권, 1998. 2 강진양, 신길섭

약용탄 - Cataplasm의 제제화, 생명과학지(삼육대논문집), 4권, 1998. 2 강진양

약용탄 - Cataplasm의 제제화, 생명과학지(삼육대논문집), 4권, 1998. 2 강진양

Controlled releas and Bioavailability of Piraceta, 한국 약학회지 제 28권, 1998. 2 강진양, 서성훈, 이경태
프레드리솔론패취의 피부특성에 관한 실험, 생명과학지(삼육대학논문집), 5권, 1999. 2 강진양

황토파프 특허출원(1999. 12)

황토의 산화철(Fe2O3) 함량과 일반적 성질, 한국 약제학회지, 30권, 2000. 9 강진양, 김인규, 서성훈

섹심캅셀의 생물학적동등성시험, 화학요법지, 2000. 12 강진양, 서성훈, 강진한, 이경태

The Case-Control Studies Between The Single Nucleotide Polymorphisms of the Human SA and MTHFR Gene and Htpertension in Korean Population Environmental mutagens & calcinogens, 2002. 9. 26 강진양, 하남주, 강병룡

The Protein Polymorphism of Hapoglobin in Korean Elite Athletes Medical principle & practice, 2002. 12 강진양, 이강오, 강병룡

Muscle-Specific Creatine Kinase Gene Polymorphisms in Korean Elite Athletes, 한국독성학회, 2003. 6 강진양, 하남주, 최성숙

The Mitochondrial DNA 5178 A/C Polymorphism in Elite Korean Male Athletes Korean journal of genetics, 2003. 9. 30 강진양, 하남주, 강병룡

Association Study Between Genetic Polymorphisms in Inter lukin-1 Gene Family and Adult Periodontitis in Korean 한국독성학회, 2004. 12 강진양, 이강오, 강병룡

Identification of Lactobacillus ruminus SPM0211 Isolated from Healthy Koreans and Its Antimicrobial Activity against Some Pathogens, Archives of Pharmacal Research Vol.28, No.6, 대한약학회, 2005. 6. 30

Human G-protein B3 Subuit C825T Polymorphism is Associated with Serum Total Cholesterol and L D L -Cholesterol Levels in Koreans, Integrative Biosciences
Vol. 9, 한국동물학회, 2005. 7. 11

Safety Assessment of Potential Lactic Acid Bacteria Bifidobacterium longum SPM1205 Isolated from Healthy Koreans, The Journal of Microbiology Vol.43, No.6, The Microbiological Society of Korea, 2005. 7. 11

FAA와 HPMC을 위용한 Metformin HCI 함유 GR 타입 정제에 의한 용출을 개선,
약제학회지 제38권 제1호 51-55P, 한국약제학회, 2008. 2. 21

바클란정(바클로펜 10mg)에 대한 태평양바클로펜정의 생물학적동등성, Bioequivalence of Taepyungyang Baclofen Tablet to Baclan™ Table(Baclofen 10 mg), 약제학회지 제37권 제4호 249-254p, 한국약제학회, 2007. 6. 28

Effect of chromosomal variations on pharmacokinetic activity of zolpidem in healthy volunteer: An array-based comparative genomic hybridization study,
Biochemical and Biophysical Research Communications 356 981-987p,
Biochemical and Biophysical Research Communications, 2007. 3. 26

LC-MS/MS를 이용한 제일크라비트정(레보플록사신 100mg)에 대한 레사신정 100mg 의 생물학적 동등성, 약제학회지(2008) 제38권 제4호 pp.269~275, 한국약제학회, 2008. 9. 27

PEO와 HPMC를 이용한 티니다졸 정제의 용출율 개선, 약제학회지(2009) 제39권 제1호 pp.7~12, 한국약제학회, 2008. 12. 6

Development of Nifedipine-loaded Coated Gelatin Microcapsule as a Long Acting Oral Delivery, Arch Pharm Res Vol.32, No.1 pp.127-132, Archives of Pharmacal Research. 2009. 2. 2.

경력

삼육대학교 약학과 교수
한국약제학학회 출판위원
삼육대학교 교무처장

학력

1988.3 - 1992.2 삼육대학교 약학사
1996.8 - 1998.8 가톨릭대학교 대학원 의학석사(병리학 전공)
1998.8 - 2002.2 가톨릭대학교 대학원 의학박사(병리학 전공)

논문

[국제 전문 학술지]

Kim TH, Chae GT, Kang TJ. The relation between NOD2 and IL-1β secretion in mouse tissues infected with Mycobacterium leprae. Cytokine, 2011 (Submitted)

Kang TJ, Moon JS, Lee SY, Yim DS, Polyacetylene Compound from Cirsium japonicum var. ussuriense inhibits the LPS-induced inflammatory reaction via suppression of NF-kB activity in RAW 264.7 cells Biomol & Ther. 2011; 19(1) (in press)

Lee GS, Choi JY, Choi YJ, Yim DS, Kang TJ*, Cheong JH*, The wound healing effect of Hydnocarpi Semen extract on ulcer in diabetic mice. Biomol & Ther. 2010; 18 (3): 329-335
* Co-corresponding authors

Kang TJ, Lee GS, Kim SK, Jin SH, Chae GT, Comparison of Two Mice Strains, A/J and C57BL/6, in Caspase-1 Activity and IL-1β Secretion of Macrophage to Mycobacterium leprae Infection. Mediators of Inflammation, vol. 2010, Article ID 708713, 5 pages, 2010. doi:10.1155/2010/708713 (Open Access Journal)

Kang TJ, Lee SY, Singh RP, Agarwal RA, Yim DS. Anti-tumore activity of oxypeucedanin from Ostericum koreanum against human prostate carcinoma DU145 cells. Acta Oncologica 2009; 48 (6): 895-900.

Li X-L, Ezelle HJ, Kang TJ, Zhang L, Shirey KA, Harro J, Hasday J, Mohapatra S, Crasta OR, Vogel SN, Cross AS, Hassel BA. An essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity. PNAS. 2008; 105 (52): 20816-20821.

Chen WH, Kang TJ, Bhattacharjee AK, Cross AS. Intranasal administration of a detoxified endotoxin vaccine protects mice against heterologous Gram-negative bacterial pneumonia. Innate Immunity. 2008; 14 (5): 269-278.

Rifat S, Kang TJ, Mann D, Zhang L, Puche A, Stamatos NM, Goldblum SE, Brossmer R, Cross AS. Expression of sialyltransferase activity on intact human neutrophils. Journal of Leukocyte Biology. 2008; 84 (4): 1075-1081.

Kang TJ, Basu S, Zhang L, Thomas KE, Vogel SN, Baillie L, Cross AS. Bacillus anthracis spores and lethal toxin induce IL-1β via functionally distinct signaling pathways. European Journal of Immunology. 2008; 38 (6): 1574-1584.

Cole LE, Santiago A, Barry E, Kang TJ, Shirey KA, Roberts ZJ, Elkins KL, Cross AS, Vogel S. Macrophage Proinflammatory Response to Francisella tularensis Live Vaccine Strain Requires Coordination of Multiple Signaling Pathways. J. Immunol. 2008; 180 (10): 6885-6891.

Im JS, Kang TJ, Lee SB, Kim CH, Lee SH, Venkataswamy MM, Serfass ER, Chen B, Illarionov PA, Besra GS, Jacobs WR Jr., Chae GT, Porcelli SA, Alteration of the relative levels of iNKT cell subsets is associated with chronic mycobacterial infections. Clinical Immunology. 2008; 127 (2): 214-224.

Brahmbhatt TN, Darnell SC, Carvalho HM, Sanz P, Kang TJ, Bull RL, Rasmussen SB, Cross AS, O’Brien AD. Recombinant exosporium protein BclA of Bacillus anthracis effective as a booster for mice primed with suboptimal amounts of protective antigen. Infection and Immunity 2007; 75 (11): 5240-5247. (2007. 11)

Weaver J*, Kang TJ*, Raines K, Cao G, Baillie L, Rosen G, Cross AS. Protective Role of Bacillus anthracis Exosporium in Macrophage-Mediated Killing by Nitric Oxide. Infection and Immunity. 2007; 75 (8). 75 (8): 3894-3901* equally contributed

Basu S, Kang TJ, Chen WH, Fenton MJ, Baillie L, Hibbs S, Cross AS. Role of Bacillus anthracis (BA) Spore Structures in Macrophage Cytokine Responses. Infection and Immunity. 2007; 75(5): 2351-2358. )

Yeum CU, Park SY, Kang TJ, Han H, Chae GT. Effects of vitamin K2on adipogenic and osteogenic differentiation in mesenchymal stem cells from human umbilical cord blood. Key Engineering Materials. 2007; 342-343: 121-124.

Joshi VD, Kalvakolanu DV, Chen W, Zhang L, Kang TJ, Thomas TE, Vogel SN, Cross AS. A role for STAT1 in the regulation of lipopolysaccharide-induced interleukin-1β expression. Journal of Interferon and Cytokine Research. 2006; 26 (10): 739-747.

Raines KW, Kang TJ, Hibbs S, Cao GL, Weaver J, Tsai P, Baillie L, Cross AS, Rosen GM. Importance of Nitric Oxide Synthase in the Control of Infection by Bacillus anthracis. Infection and Immunity. 2006; 74(4): 2268-2276.

Kang TJ, Fenton MJ, Weiner MA, Hibbs S, Basu S, Baillie L, Cross AS: Murine macrophages kill the vegetative form of Bacillus anthracis. Infection and Immunity. 2005; 73(11): 7495-7501.

You EY, Kang TJ, Kim SK, Lee SB, Chae GT. Mutations in genes related to drug resistance in Mycobacterium leprae isolates from leprosy patients in Korea. Journal of Infection 2005; 50(1): 6-11.

Kang TJ, Yeum CE, Lee H, Rho SH, Han H, Chae GT. Growth kinetics of mesenchymal stem cells from bone marrow and umbilical cord blood. Acta Haematologica 2004; 112(4): 230-233.

Kang TJ, Yeum CE, Kim BC, You EY, Chae GT. Differential production of interleukin-10 and interleukin-12 in mononuclear cells from leprosy patients with a Toll-like receptor 2 mutation. Immunology. 2004; 112(4): 674-80.

Kim BC, Kang TJ, Yeom JE, Chae GT. Tissue-specific down-regulation of RIPK2 in Mycobacterium leprae infected nu/nu mice. Mediators of Inflammation. 2004; 13(1): 51-52

Kang TJ, Kim SK, Lee SB, Chae GT, Kim JP, Ko YH. Comparison of two different PCR amplification products (the 18 kDa Protein Gene vs. RLEP Repetitive Sequence) in the diagnosis of Mycobacterium leprae. Clinical and Experimental Dermatology. 2003; 28(4): 420-424

Lee SB, Kim BC, Jin SH, Park YG, Kim SK, Kang TJ, Chae GT. Missense mutation of the interleukin-12 receptor beta 1 (IL-12RB1) and interferon-gamma receptor 1 (IFNGR1) genes are not associated with susceptibility to lepromatous leprosy in Korea. Immunogenetics. 2003; 55(3): 177-181

Kim SK, Lee SB, Kang TJ, Chae GT. Detection of gene mutations related with drug resistance in Mycobacterium lepraefrom leprosy patients using Touch-Down (TD) PCR. FEMS Immunol. Med. Microbiol. 2003; 26(1-2): 27-32

Kang TJ, Lee SB, Chae GT. A polymorphism of TLR2 is associated with IL-12 production in lepromatous leprosy. Cytokine. 2002; 20(2): 56-62

Chae GT, Kim MJ, Kang TJ, Lee SB, Shin HK, Kim JP, Ko YH, Kim SH, and Kim NH. DNA PCR and RT-PCR for the 18kDa gene of Mycobacterium leprae to assess the efficacy of multi-drug therapy for leprosy. J. Med. Microbiol. 2002; 51(5): 417-422.

Chae GT, Lee SB, Kang TJ, Shin HK, Kim JP, Ko YH, Kim SH, and Kim NH. Typing of clinical isolates ofMycobacterium leprae and their distribution in Korea. Leprosy Review. 2002; 73(1): 41-46.

Kang TJ, You JC, Chae GT. Identification of catalase-like activity from Mycobacterium leprae and the relation between catalase and isonicotinic acid hydrazide(INH). J. Med. Microbiol. 2001; 50(8): 675-681.

Kang TJ, Chae GT. Detection of TLR2 mutation in lepromatous leprosy patients. FEMS Immunol. Med. Microbiol. 2001; 31(1): 53-58.

Lee SB, Kim SK, Kang TJ, Chae GT, Chun JH, Shin HK, Kim JP, Ko YH, and Kim NH. The prevalence of mutations in the folP1 gene of the Mycobacterium leprae in isolates from Korea in association with clinical resistance to Dapsone. Annals of Tropical Medicine and Parasitology. 2001; 95 (4): 419-432.

[국내 전문 학술지]

Lee GS, Pena ID, Choi JH, Choi JY, Yoon SY, Kang TJ, Oh SK, Cheong JH. Effect of SPZZC, a Composition of Herb Extracts, on Atopic Dermatitis in BALB/c and NC/Nga Mouse. Yakhak Hoeji. 2008; 52 (3): 232-239.

강태진. 알코올성 간질환과 자연면역반응. 한국알코올과학회지 2007; 8: 77-92

김병철, 강태진, 채규태. 나균 감염과 RIPK2의 연관성 연구. 대한나학회지 2003; 36(2): 23- 29.

김세곤, 강태진, 김병철, 채규태. 나균감염에 관련된 Phagosomal Coat Protein (TACO)의 C-terminal region (exon 9～11)의 point mutation. 대한나학회지 2003; 36(1): 11- 26.

이성범, 유은영, 김세곤, 강태진, 김종필, 고영훈, 채규태. 복합 항나제의 치료에 내성을 보이는 한국인 나환자에서 분리한 나균에서의 folP1, rpoB, gyrB 유전자의 돌연변이에 대한 연구. 대한나학회지 2003; 36(1): 3-9.

김세곤, 이성범, 강태진, 채규태. 나환자 진단 및 약제내성 검색에 있어서 TD-PCR의 적용. 대한나학회지 2001; 34(2): 13-21.

강태진, 이성범, 채규태. 나병병형에 따른 IL-12 생성에 미치는 TLR2 변이의 영향. 대한나학회지 2001; 34(2): 3-12.

강태진, 이성범, 채규태. 누드 마우스로부터 나균 세포추출물 분리를 위한 최적화 방법에 관한 연구. 대한나학회지. 2001; 34(1): 47-56.

채규태, 이성범, 강태진, 김종필, 고영훈. 한센병의 감수성 및 그 병형에 관련된 HLA-A,B 및 DRB1 유전자의 규명. 대한나학회지. 2000; 33(2): 67-78.

강태진, 채규태. Isonizid 활성에 있어서 Mycobacteria의 katG gene의 역할. 대한나학회지. 2000; 33(2): 55-66.

김세곤, 김민주, 강태진, 채규태. 나균감염 대식세포에서 Rifampin의 H2O2억제효과. 대한나학회지. 1997; 30(2): 41-48

경력

1992.3 - 1992.7 삼육대학교 약학과 조교
1993.7 - 1996.6 국군포항병원 약제과장
2002.2 - 2004.7 가톨릭대학교 의과대학 병리학교실 박사후 연구원
2003.1 - 2003.2 미국 네바다주립대학교 방문연구원
2004.8 - 2007.7 미국 메릴랜드주립대학교 의과대학 박사후 연구원
2006.1 - 현재 The Society for Leukocyte Biology (미국) 정회원
2007.1 - 현재 대한약학회 정회원, 사업간사, 총무간사
2007.9 - 현재 삼육대학교 전임강사, 조교수
2008.1 - 현재 한국알코올과학회 정회원, 이사
2008.1 - 현재 American Society for Microbiology (미국) 정회원
2008.1 - 현재 한국응용약물학회 정회원, 총무간사
2008.1 - 현재 대한면역학회 정회원, 편집위원
2008.7 - 2009.7 체육과학연구원 생활체육지도자연수원 외래강사
2010.1 - 2012.1 중앙약사심의위원회 위원(전문가)

학력

1983년 (학사) 삼육대학교 약학
1985년 (석사) 서울대학교 미생물학
1993년 (박사) Philadelphia Coll. of Pharm.& Sci. 면역학

논문

Young-Ran Lee, Young-Hee Lee, Sun-A Im, In-Ho Yang, Ghe Whan Ahn, Kyungjae Kim, and Chong-Kil Lee (2010) Biodegradable Nanoparticles Containing TLR3 or TLR9 Agonists Together with Antigen Enhance MHC-restricted Presentation of the Antigen. Arch.Pharm.Res.33(11),1859-1866.

Seulmee Shin, Yoonhee Park, Seulah Kim, Hee-Eun Oh, Young-Wook Ko, Shinha Han, Seungjeong Lee, Chong-Kil Lee, Kyunghae Cho and Kyungjae Kim (2010) CordycepsmilitarisenhancesMHC-restrictedantigenpresentationviatheinducedexpressionofMHCmoleculesandproductionofcytokines.Immunenetwork10(4)135-143.

Hyunseok Kong, Sungwon Lee, Seulmee Shin, Jeunghak Kwon, Jo,EunjuShin,Kyu-SukShim,Young-InPark,Chong-KilLee,KyungjaeKim(2010)Down-regulationofadipogenesisandhyperglycemiaindiet-inducedobesitymousemodelbyAloeQDM.Biomolecules$Therapeutics,18(3),336-342.

Hyun-Jin Kim, Young-Hee Lee, Sun-A Im, Kyungjae Kim and Chong-Kil Lee (2010) Cyclooxygenase inhibitors, Aspirin and Ibuprofen, inhibit MHC-restricted antigen presentation in dendritic cells. Immunenetwork10(3)92-98.

Seulmee Shin, Jeonghak Kwon, Sungwon Lee, Hyunseok Kong, Seungjeong Lee, Chong-Kil Lee, Kyunghae Cho, Nam-Joo Ha, Kyungjae Kim (2010) Immunostimulatory effects of CordycepsmilitarisonmacrophagesthroughtheenhancedproductionofcytokinesviatheactivationofNF-κB.Immunenetwork10(2)55-63.

Sun-A Im, Young-Ran Lee, Young-Hee Lee, Myung-Koo Lee, Young In Park, Sungwon Lee, Kyungjae Kim, and Chong-Kil Lee (2010) InVivoEvidenceoftheImmunomodulatoryActivityofOrallyAdministeredAloeveraGel.ArchivesofPharmacalResearch33(3) 452-456.

Seulmee Shin, Sunhee Moon, Yoonhee Park, Jeonghak Kwon, Seungjeong Lee, Chong-Kil Lee, Kyunghae Cho, Namjoo Ha, and Kyungjae Kim (20009) Role of cordycepin and adenosine on the phenotypic switch of macrophages via induced anti-inflammatory cytokines. Immunenetwork9(6)255-263

Eunhye Back, Dokyung Lee, Hyangmi An, Mijin Kim, Kyungjae Kim, Kangoh Lee, and Namjoo Ha (2009) Antibiotic Resistance and assessment of Food-borne Pathogenic Bacteria in Frozen Foods. ArchivesofPharmacalResearch32(12) 1749-1757.

Jae Seung Kang, Seyeon Bae, Hangrae Kim, Yeong Seok Kim, Daejin Kim, Byung Joo Cho, Han-Kwang Yang, Young-Il Hwang, Kyungjae Kim, Hong Suk Park, Doukho Hwang, Daeho Cho, and Wang Jae Lee (2009) Interleukin-18 increases metastasis and immunr escape do stomach cancer via the down-regulation of CD70 and maintenance of CD44. CarcinogenesisDec200930(12)1987-1996

Seulmee Shin, Sungwon Lee, Jeonghak Kwon, Sunhee Moon, Seungjeong Lee, Chong-Kil Lee, Kyunghae Cho, Nam-Joo Ha, and Kyungjae Kim (2009) Cordycepin Suppresses Expression of Diabetes Regulating Genes by Inhibition of Lipopolysaccharide-induced Inflammation in Macrophages. Immunenetwork 9(3)98-105.

Jae Kwon Lee, Young-Ran Lee, Young-Hee Lee, Kyungjae Kim and Chong-Kil Lee (2009) Production of TGF-β1 as a Mechanism for Defective Antigen-presenting Cell Function of Macrophages Generated in vitro with M-CSF. Immune network 9(1) 27-32.

Kwanghee Kim, Hyunyul Kim, Jeunghak Kwon, Sungwon Lee, Hyunseok Kong, Nam Joo Ha, Sun-A Im, Young-Hee Lee, Young-Ran Lee, Sun-Tack Oh, Tae Hyung Jo, Young In Park, Chong-Kil Lee, Kyungjae Kim (2009) Hypoglycemic and hypolipidemic effects of processed Aloe vera gel in a mouse model of non-insulin dependent diabetes mellitus. Phytomedicine 16 856-863

Do kyung Lee, Byung Yong Kang, Myung Jun Chung, Kang Oh Lee, Kyungjae Kim and Nam Joo Ha (2008) Genomic fingerprinting patterns of Bifidobacteria isolated from healthy Korean using ERIC-, TAP-, and BOX-PCR. Journal of Environ. Toxicol. 23(1) 1-9.

Do Kyung Lee, Seok Jang, Mi Jin Kim, Jung Hyun Kim, Myung Jun Chung, Kyungjae Kim and Nam Joo Ha (2008) Anti-proliferative effects of BifidobacteriumalolescentisSPM0212extractonhumancoloncancercelllines.BMCCancer8:310.

Yuna Kim, Dokyung Lee, Donghyun Kim, Jooyong Cho, Jaewook Yang, Myungjun Chung, Kyungjae Kim and Namjoo Ha (2008) Inhibition of proliferation in colon cancer cell lines and harmful enzyme activity of colon bacteria by BifidobacteriumadolescentisSPM0212.Archives of Pharmacal Research 31(4) 468-473

Shinha Han, Kwanghee Kim, Youngcheon Song, Hyunyul Kim, Jeunghak Kwon, Young-Hee Lee, Chong-Kil Lee, NamjooHaandKyungjaeKim(2008)Auranofin,animmunosuppressivedrug,inhibitsMHCclassIandMHCclassIIpathwaysofantigenpresentationindendriticcells.ArchivesofPharmacalResearch31(3), 370-376.

Shinha Han, Kwanghee Kim, Hyunyul Kim, Jeunghak Kwon, Young-Hee Lee, Chong-Kil Lee2YoungcheonSong,Sang-JinLee,NamjooHa,KyungjaeKim (2008) Auranofin Inhibits Overproduction of Pro-inflammatory Cytokines, Cyclooxygenase Expression and PGE2Productionin Macrophages. Archives of Pharmacal Research31(1), 67-74.

Turmunkh Gerelchuluun, Young-Hee Lee, Young-Ran Lee, Sun-A Im, Sukgil Song, Jeong Sook, Kun Han, Kyungjae Kim, and Chong-Kil Lee (2007) Dendritic cells process antigens encapsulated in a biodegradable polymer, poly(D,L-lactide-co-glycolide), via and alternative class MHC processing pathway.


Se Hee Park, Yun A Kim, Dokyung Lee, Sangjin Lee, Myungjun Chung, Byung Yong Kang, Kyungjae Kim and Namjoo, Ha (2007) Antibacterial activity and macrophage activation of lactic acid bacteria. JournalofEnviron.Toxicol. 22(4) 287-297.

Young-Hee Lee, Young-Ran Lee, Sun-A Im, Sun-ImPark,Ki-HyangKim,TurmunkhGerelchuluun,SukgilSong,KyungjaeKim,andChong-KilLee(2007)CalcineurininhibitorsblockMHC-restrictedantigenpresentationinvivo.JournalofImmunology179,5711-5716.

Do Kyung Lee, Yuna Kim, KunSupPark,Jae Wook Yang, Kyungjae Kim, and Nam Joo Ha (2007) Antimicrobial activity of Mupirocin, Daptomycin, Linezoid, Quinupristin/Dalfopristin and Tigecycline against Vancomycin-Resistant Enterococci (VRE) from clinical Isolates in Korea(1998and2005).JournalofBiochemistryandMolecularBiology40(6):881-887

Hyunyul Kim, Kwanghee Kim, Shinha Han, Seongjung Lee, Jeunghak Kwon, Sungwon Lee, and Kyungjae Kim (2007) Activation of macrophages by the components produced fromCodycepsmilitaris.Immune Network 7(2):57-65

Shinha Han, Kwanghee Kim, Hyunyul Kim, Jeunghak Kwon, Chong-Kil Lee, Namjoo Ha, and Kyungjae Kim (2007) Mizoribine inhibits production of pro-inflammatory cytokines and PGE2 in macrophages. Immune Network 7(1):31-38

Jaewook Yang, Dokyung Lee, Yuna Kim, Byungyong Kang, Kyungjae Kim, and Namjoo Ha (2007) Occurrence of the Van genes in enterococcus faecalis and Enterococcus faecium from clinical isolates in Korea. ArchivesofPharmacalResearch30(3),329-336.

경력

1996~1997 National Institute of Health Postdoctoral Research Fellow 1997~1998 National Cancer Institute Guest Research Fellow 1999.06.~1999.8. National Cancer Institute Guest Research Fellow 2000.06.~2000.8. National Cancer Institute Guest Research Fellow 2003.12.~2005.2. Sidney Kimmel Cancer Center Senior Scientist
1999.03.~현재 삼육대학교 Full Professor
2011.01.~현재 Editor in Chief in ‘Immune Network‘

학력

1995.03 - 1999.02 삼육대학교 약학과[학사]
2001.09 - 2004.08 숙명여자대학교 임상약학대학원 임상약학 전공 [석사]
2008.03 – 2010.08 숙명여자대학교 임상약학대학원 사회약학 전공 [석사]
2011.09 – 2015.02 성균관대학교 약학대학 보건사회약학 전공 [박사]

논문

[학술지]

- Kim HL, Kim D, Jang EJ, Lee MY, Song HJ, Park SY, Cho SK, Sung YK, Choi CB, Won S, Bang SY, Cha HS, Choe JY, Chung WT, Hong SJ, Jun JB, Kim J, Kim SK, Kim TH, Kim TJ, Koh E7, Lee H, Lee HS, Lee J, Lee SS, Lee SW, Park SH, Shim SC, Yoo DH, Yoon BY, Bae SC, Lee EK. (2016) Mapping health assessment questionnaire disability index (HAQ-DI) score, pain visual analog scale (VAS), and disease activity score in 28 joints (DAS28) onto the EuroQol-5D (EQ-5D) utility score with the KORean Observational study Network for Arthritis (KORONA) registry data. Rheumatol Int. 36(4):505-13

- Song HJ, Lee EK, Lee JA, Kim HL, Jang KW. (2014) Tumour Biol. The addition of mifamurtide to chemotherapy improves lifetime effectiveness in children with osteosarcoma: a Markov model analysis. 35(9):8771-8779

- Lee MY, Kang HJ, Park SY, Kim HL, Han E, Lee EK. (2014) Cost-effectiveness of tolvaptan for euvolemic or hypervolemic hyponatremia. Clin Ther. 36(9):1183-94

- Kim HL, Lee MY, Park SY, Park SK, Byun JH, Kwon S, Lee EK. (2014) Comparative effectiveness of cycling of tumor necrosis factor-α (TNF-α) inhibitors versus switching to non-TNF biologics in rheumatoid arthritis patients with inadequate response to TNF-α inhibitor using a Bayesian approach. Arch Pharm Res. 37(5):662-70

- 박선경, 김혜린, 이민영, 김안나, 이의경. (2015) Conventional DMARDs 치료에 실패한 류마티스 관절염 환자에서 Biologic DMARDs의 임상적 효과 비교: 베이지안 네트워크 메타분석. 한국임상약학회지 25(1):9-17

- 김혜린, 이재현. (2013) 사용량·약가 연동제 시행 주요 외국의 현황 조사·연구. J Health Tech Assess. 1:61-68

- 김혜린, 이진이, 이의경. (2011) 공개경쟁입찰을 통해 구매한 의약품 가격의 결정요인: 1개 국공립병원 사례를 중심으로. 보건경제와 정책연구. 17(2):77-97





[연구보고서]

- 현행 위험분담계약제의 운영에 대한 문제점과 개선방향에 대한 연구 (2016.02)

- Sovaldi/Harvoni의 경제성평가 연구 (2015.07)

- 우리나라와 OECD 국가의 약가수준 비교 (2014.06)

- 적정기준가격제 시행방안 연구 (2012.05)

- 신약연구개발 촉진을 위한 각국의 보험약가 정책 연구 (2011.12)

- 주요 5개국의 보험약가 관리제도 (2011.12)

- 건성안 치료에서의 Diquas 약물경제성 평가 연구 (2011.12)

- 혈우병 치료에서의 Kogenate FS 약물경제성 평가 연구 (2011.07)

경력

2000.03 – 2003.03 서울대학교병원 약제부 약무직
2003.03 - 2010.10 분당서울대학교병원 약제부/물류자산팀 과장
2010.11 - 2012.02 숙명여자대학교 의약정보연구소 연구원
2015.03 - 2016.02 성균관대학교 약학연구원 선임연구원
2013.03 – 2015.12 삼육대학교 약학과 외래강사
2016.03 - 현재 삼육대학교 약학과 조교수

학력

1993년 (학사) 삼육대학교 약학
1995년 (석사) 서울대학교 약품분석학
2002년 (박사) 서울대학교 약품분석학

논문

[학술지]
● G.S.Lee, B.S.Tan-Lee, M.Kim, K.U.Dong, J.Kim, G.Y.Yu, J.Han, H.S.Ko, I.H.Park, J.H.Cheong : Stress related activities of Sun-ginseng in SD Rats and ICR Mice, J. Appl. Pharmacol., 12(4), 242-249 (2004)
● X.L.Piao, I.H.Park, S.H.Baek, H.Y.Kim, M.K.Park, J.H.Park : Antioxidative activity of furanocoumarins isolated from Angelicre dahuricae, J. Ethnopharmacology, 93, 243-246 (2004)
● I.H.Park, L.Z.Piao, S.W.Kwon, Y.J.Lee, S.Y.Cho, M.K.Park, J.H.Park : Cytotoxic dammarane glycosides from processed ginseng, Chem. Pharm. Bull., 50(4), 538-540 (2002)
● I.H.Park, J.M.Kim, L.Z.Piao, S.W.Kwon, N.Y.Kim, S.B.Han, M.K.Park, J.H.Park : Four new acetylated ginsenosides from processed ginseng, Arch. Pharm. Res., 25(6), 837-841 (2002)
● I.H.Park, N.Y.Kim, S.B.Han, J.M.Kim, S.W.Kwon, H.J.Kim, M.K.Park, J.H.Park : Three new dammarane glycosides from heat processed ginseng, Arch. Pharm. Res., 25(4), 428-432 (2002)
● S.W.Kwon, S.B.Han, I.H.Park, J.M.Kim, M.K.Park, J.H.Park : Liquid chromatographic determination of less polar ginsenosides in processed ginseng, J. Chromatography A, 921, 335-339 (2001)
● M.K. Park, J.H. Park, S.B.Han, Y.G.Shin, I.H.Park : High performance liquid chromatographic analysis of ginseng saponins using an evaporative light scattering detector, J. Chromatography A, 736, 77-82 (1996)
● M.K. Park, J.H. Park, S.B.Han, I.H.Park : Analysis of organic germanium, Ge-132, J. Kor. Soc. Anal. Sci., 8(3), 371-374 (1995)

[학술회의 Proceeding]
● M.Sugahara, I.H.Park, K.Pichai (2003) The universality of the aggregational activity of oriental honeybee to the orchid Kinryouhen, Proceedings of the 74th annual meeting of Zoological Society of Japan, Abstr. p.167, Hakodate, Japan, Sep. 17-19
● S.W. Kwon, N.Y.Kim, I.H.Park, S.B.Han, J.M.Kim, J.H.Park, M.K.Park (2000) Seven new dammarane glycosides from heat processed ginseng, Proceedings of the spring convention of the pharmaceutical society of Korea Abstr., p.255 The 50th Convention of the Pharmaceutical Society of Korea, Seoul, Oct. 17-19
● E.J.Cho, J.H.Park, I.H.Park, S.H.Jun, X.L.Piao, M.K.Park (2000) Analysis of the compounds in Citrus Junos, Proceedings of the spring convention of the pharmaceutical society of Korea Abstr., p.254 The 50th Convention of the Pharmaceutical Society of Korea, Seoul, Oct. 17-19

[저 서]
● 약품정량분석 연습, 박일호 외 22인(약품정량분석분과회), 신일상사 (2004)
● J.H.Park, W.Y.Kim, S.E.Hong, I.H.Park, M.K.Park : Identification of herbal medicines using pyrolysis mass spectrum, Progress of Pharmaceutical analysis I, pp. 126-151, The Pharmaceutical Society of Korea (1998)

[특 허]
● 산소를 이용한 개량 홍삼의 제조 방법 : 박일호 외 6인, 대한민국 등록 0454414, 2004. 10.15
● 가공인삼 추출물 함유 피부질환 치료제 조성물 : 박일호 외 4인, 대한민국 출원(2002-0016900), 2003.10.8
● 신규한 다마란 유도체, 그 제조 방법 및 그를 활성성분으로 포함하는 뇌신경세포 보호제 : 박일호 외 6인, 대한민국 출원 (2000-0068192), 2002.5.23
● 항암성 인삼사포닌, 그 제조방법 및 그를 활성성분으로 함유하는 항암제 조성물 : 박일호 외 8인, 대한민국 등록 0316567, 2001.11.22

[연구분야]
● Liquid chromatography-Mass spectrometer를 이용한 의약품제제 및 천연물 활성성분의 분리 및 구조 동정

경력

1996. 9. ~ 2002. 8. 삼육대학교 약학과 시간강사
1999. 3. ~ 2000. 3. 서울대학교 약학대학 종합약학연구소 보조연구원
2001. 8. ~ 2002. 6. ㈜진생사이언스 연구소 선임연구원
2002. 6. ~ 2004. 2. Suntory Bioorganic research center(Jap) Postdoc.
2004. 3. ~ 현재 삼육대학교 약학과 전임강사, 조교수

학력

1995.03~1999.02 삼육대학교, 약학과, 학사
1999.03~2001.02 삼육대학교 대학원 약학과, 석사
2008.03~2012.08 강원대학교 약학과, 박사

논문

PUBLICATIONs (최근 5년)
Yu-Byoung Chae, Sung-Yeop Kim, Chin-Yang Kang, and Jun-Bom Park, Effect of Hydrophilic and Hydrophobic Polymers on the Sustained-release Sarpogrelate HCl from Matrix Tablets, J. Pharm. Soc. Korea 2020, 64(6), 446-453

Hee Jo Yoo, Se-Jung Hwang, Jeong-Hun Lee, Wang-Seo Shim, Yun-Woong Choi, Sang Min Cho, Eun Kyoung Chung*, Jun-Bom Park*, Kyung-Tae Lee*, Development and Validation of an LC-MS/MS Assay to Quantitate 2′,4′,6′-Trihydroxyacetophenone in Rat and Dog Plasma and its Application to a Pharmacokinetic Study, Molecules 2020, 25, 4373

Sung-Min Choi, Sung-Hoon Lee, Chin-Yang Kang and Jun-Bom Park, Preparation of Hot-Melt Extruded Dosage Form for Enhancing Drugs Absorption Based on Computational Simulation, Pharmaceutics, 2020, 12, 757

Byung-Cheol Oh, Gang Jin, Chulhun Park, Jun-Bom Park, Beom-Jin Lee, Preparation and evaluation of identifiable quick response (QR)-coded orodispersible films using 3D printer with directly feeding nozzle, International Journal of Pharmaceutics, 2020, 584, 119405

Ilhwan Hwang, Vanamane Renuka, Ju-Hyun Lee, Kwon-Yeon Weon, Chin-Yang Kang, Beom-Jin Lee and Jun-Bom Park, Preparation of Celecoxib Tablet by Hot Melt Extrusion Technology and Application of Process Analysis Technology to Discriminate Solubilization Effect, Pharmaceutical Development and Technology, 2020, 25(5), 525-534

Bhupendra Raj Giri, Eon Soo Song, Jaewook Kwon, Ju-Hyun Lee, Jun-Bom Park and Dong Wuk Kim, Fabrication of Intragastric Floating, Controlled Release 3D Printed Theophylline Tablets Using Hot-Melt Extrusion and Fused Deposition Modeling, Pharmaceutics, 2020, 12, 77

Dayoung Kim, Chulhun Park, Nileshkumar M. Meghani, Thao T.D. Tran, Phuong H.L. Tran, Jun-Bom Park, Beom-Jin Lee, Utilization of a fattigation platform gelatin-oleic acid sodium salt conjugate as a novel solubilizing adjuvant for poorly water-soluble drugs via self-assembly and nanonization, International Journal of Pharmaceutics, 2020, 575, 118892

Sung-min Choi, Yong-Koo Jeon, Ju-Hyun Lee, Chin-Yang Kang, and Jun-Bom Park, Solubility Enhancement of Poorly Water-Soluble Drugs by Hot-Melt Extrusion Technology and Effects of Surfactant on Dissolution Test, J. Pharm. Soc. Korea, 2019, 63(6), 384-389

Shrawani Lamichhane, Jun-Bom Park, Dong Hwan Sohn and Sangkil Lee, Customized Novel Design of 3D Printed Pregabalin Tablets for Intra-Gastric Floating and Controlled Release Using Fused Deposition Modeling, Pharmaceutics, 2019, 11, 564-577

Chulhun Park, Nileshkumar M. Meghani, Yongkwan Shin, Euichaul Oh, Jun-Bom Park, Jing-Hao Cui, Qing-Ri Cao, Thao Truong-Dinh Tran, Phuong Ha-Lien Tran and Beom-Jin Lee, Investigation of Crystallization and Salt Formation of Poorly Water-Soluble Telmisartan for Enhanced Solubility, Pharmaceutics, 2019, 11, 102-117

Kyu-Yeol Nama, Sang Min Cho, Youn-Woong Choi, Chulhun Park, Nileshkumar M. Meghani, Jun-Bom Park, Beom-Jin Lee, Double controlled release of highly insoluble cilostazol using surfactant- driven pH dependent and pH-independent polymeric blends and in vivo bioavailability in beagle dogs, International Journal of Pharmaceutics, 2019, 558, 284-290

Changmin Kang, Ju-Hyun Lee, Dong-Wook Kim, Beom-Jin Lee, and Jun-Bom Park, Preparation of Sustained Release Tablet with Minimized Usage of Glyceryl Behenate Using Post-Heating Method, AAPS PharmSciTech, 2018, 19(7), 3067-3075

Seung Jin Ko, Ju-Hyun Lee, Chin-Yang Kang, Jun-Bom Park, Granulation development in batch-to-batch and continuous processes from a quality by design perspective, Journal of Drug Delivery Science and Technology, 2018, 46, 34-45

Jun-Bom Park, Chulhun Park, Zhong Zhu Piao, Hardik H. Amin, Nilesh M. Meghani, Phuong H.L. Tran, Thao T.D. Tran, Jing-Hao Cui, Qing-Ri Cao, Euichaul Oh, Beom-Jin Lee, pH-independent controlled release tablets containing nanonizing valsartan solid dispersions for less variable bioavailability in humans, Journal of Drug Delivery Science and Technology, 2018, 46, 365-377

Nilesh M. Meghani, Hardik H. Amin, Chulhun Park, Jun-Bom Park, Jing-Hao Cui, Qing-Ri Cao, Beom-Jin Lee, Design and evaluation of clickable gelatin-oleic nanoparticles using fattigation-platform for cancer therapy, International Journal of Pharmaceutics, 2018, 545, 101-112

Kyung-Ho Lee · Chulhun Park · Giwon Oh · Jun-Bom Park · Beom-Jin Lee, New blends of hydroxypropylmethylcellulose and Gelucire 44/14: physical property and controlled release of drugs with different solubility, Journal of Pharmaceutical Investigation, 2018, 48, 313-321

Namhyun Baek, Ga-Hui Oh, Chulhun Park, Thuy Thi Thanh Tran, Young Joon Park, Euichaul Oh, Hau Le, Thao T.D. Tran, Jun-Bom Park, Beom-Jin Lee, Reprecipitation of poorly water-soluble cilostazol crystals using adsorbing carriers for enhanced dissolution and physicochemical modification. Journal of Drug Delivery Science and Technology, 2018, 43, 477-486

Sung-min Choi, Chin-Yang Kang, Beom Jin Lee and Jun-Bom Park, In Vitro-In Vivo Correlation Using In Silico Modeling of Physiological Properties, Metabolites, and Intestinal Metabolism. Current Drug Metabolism, 2017, 18(11), 973-982

Sultan Alshehri, Roshan Tiwari, Bader Alsulays, Eman Ashour, Abdullah Alshetaili, Bjad Almutairy, Jun-Bom Park, Joseph Morott, Bhupinder Sandhu, Soumyajit Majumdar & Michael A. Repka, Investigation of the combined effect of MgO and PEG on the release profile of mefenamic acid prepared via hot-melt extrusion techniques. Pharmaceutical Development and Technology, 2017, 22(6), 740-753

Daoqi Luo, Joo Hee Kim, Chulhun Park, Euichaul Oh, Jun-Bom Park, Jing-Hao Cui, Qing-Ri Cao, Beom-Jin Lee, Design of fixed dose combination and physicochemical characterization of enteric-coated bilayer tablet with circadian rhythmic variations containing telmisartan and pravastatin sodium. International Journal of Pharmaceutics, 2017, 523, 343-356

Ilhwan Hwang, Chin-Yang Kang, Jun-Bom Park, Advances in hot-melt extrusion technology toward pharmaceutical objectives. Journal of Pharmaceutical Investigation, 2017, 47, 123-132

Jun-Bom Park, Dong-Wook Kim, Sung-Hoon Lee, Kwon-Yeon Weon, Development of a Process Analytical Technology(PAT) method using near-infrared spectroscopy system for evaluating an active coating process for a low-dose drug. Journal of Drug Delivery Science and Technology, 2017, 39, 8-15

Jun-Bom Park, Beom-Jin Lee, Chin-Yang Kang, Roshan V. Tiwari, Michael A. Repka, Process analytical quality control of tailored drug release formulation prepared via hot-melt extrusion technology. Journal of Drug Delivery Science and Technology, 2017, 38, 51-58

Bader B. Alsulays, Vijay Kulkarni, Sultan M. Alshehri, Bjad K. Almutairy, Eman A. Ashour, Joseph T. Morott, Abdullah S. Alshetaili, Jun-Bom Park, Roshan V. Tiwari & Michael A. Repka, Preparation and evaluation of enteric coated tablets of hot melt extruded lansoprazole. Drug Development and Industrial Pharmacy, 2017, 43(5), 789-796

Abdullah S. Alshetaili, Bjad K. Almutairy, Roshan V. Tiwari, Joseph T. Morott, Sultan M. Alshehri, Xin Feng, Bader B. Alsulays, Jun-Bom Park, Feng Zhang and Michael A Repka, Preparation and Evaluation of Hot-Melt Extruded Patient-Centric Ketoprofen Mini-tablets. Current Drug Delivery, 2016, 13(5), 730-741

Eman A. Ashour, Vijay Kulkarni, Bjad Almutairy, Jun-Bom Park, Sejal Shah, Soumyajit Majumdar, Michael A. Repka, Influence of Pressurized Carbon Dioxide on Ketoprofen-Incorporated Hot-Melt Extruded Low Molecular Weight Hydroxypropylcellulose. Drug Development and Industrial Pharmacy, 2016, 42 (1), 123-130

도서 ( Books )
이범진, 손동환, 한효경, 오경택, 박준범, 김성원, 최연웅, 장희철, 김병조, 박상욱, 글로벌 개량신약 연구개발과 질환별 사업화전략. 신일서적. 2020.
이범진, 전인구, 한효경, 박준범, 임지성, 염류의약품 물성과 선택 및 응용. 신일북스 (역자). 2013.
Jun-Bom Park and Beom-jin Lee, Emerging oral controlled-release technology for optimal therapy. Future Science, 2013, Nov. 40-53.


특허 ( Patents )
Hemlata Patil, Vijay Kulkarni, Jun-Bom Park, Soumyajit Majumdar, Michael A. Repka, Systems and Methods for Preparing Lipid Nanoparticles.2014 # USSN 61/969,444.
박준범, 최성민, 생리학적 체내 동태 연구 모델링을 이용한 약제학적 조성물의 제조 방법, 10-2114550
박준범, 강창민, 친수성 약물을 포함하는 서방성 제제의 제조 방법, 2018, 제 10-1881749 호.
박준범, 강진양, 반복 고온용융 압출 성형된 약제학적 조성물의 제조 방법 및 이에 의해 제조된 약제학적 조성물, 2017, 제 10-1801476 호.
박준범, 이범진, 고온용융 압출을 이용한 저함량 약제학적 조성물의 제조방법, 2013, 제 10-1390946 호.

경력

2001.2~2004.4 초당약품 ㈜, 연구소 근무; 선임연구원
2004.5~2008.2 ㈜ 한독약품, 연구소 근무; Project Manger
2013.4~2015.02 Univeristy of Mississippi; Post-Doc Researhcer
2015.3~2021.2 삼육대학교 약학대학 약학과 조교수
2021.3~ 삼육대학교 약학대학 약학과 부교수

학회 (Society)
1) 대한약학회 정회원
2) 한국약제학회 정회원

CERTIFICATION
License for Pharmacist in Korea, Feb. 1999

학력

1984.3 - 1988.2 삼육대학교 약학사
1998.3 - 2000.2 숙명여자대학교 대학원 임상약학석사
2003.9 - 2006.9 삼육대학교 대학원 약학박사

논문

[학술지]
Seo-Yoon Choi, Yun-hee Park, Jae-youn Kim, Hye-sun Gwaka and Young-cheon Song* Fall risk in hospitalized elderly patients with drugs that induce the fall J. Kor. Soc. Health-Syst. Pharm., Vol. 29, No. 2, 182 ~ 187 (2012)

Hyun-Kyung Cha, Soo-Kyung Ryu, Young-Seol Heo, Hee-Se Kim, Young-Cheon Song* Medication counseling improvement scheme by outpatients cancer center’s medication counseling conditions and satisfaction survey J. Kor. Soc. Health-Syst. Pharm., Vol. 29, No. 2, 139 ~ 148 (2012)

Young Seol Heo, Min Kyoung Kang, Hee Se Kim, Young-Cheon Song*, Incidence, types and causes of preparation errors in intravenous chemotherapeutic agent J. Kor. Soc. Health-Syst. Pharm., Vol. 29, No. 1, 73 ~ 80 (2012)

Joo-won Chung, Yu Jin Kang, Mi Young Moon, Song Yi Moon, Hyang Min Park, Sa Mi Yang, So Jeong Yoon, Yeon Joo Lee, Eun Mi Lee, Hyo Jeong Lee, So Yeon Cho, Jae-youn Kim, and Young-Cheon Song* Preliminary study for Economic evaluation of clinical pharmacist intervention J. Kor. Soc. Health-Syst. Pharm., Vol. 28, No. 4, 327 ~ 336 (2011)

M.K. Kang, S.H. Yoon, Y.S. Heo, H.S. Kim, Y.C. Song*, Prevention of Medication Errors by Pharmacists’ Intervention of Chemotherapy, J. Kor. Soc. Health-Syst. Pharm., Vol. 28, No. 3, 288 ~ 295 (2011)

Bo-ram Sin, Heo-jung Lee, Yun-hee Park, Jae-youn Kim, Hye-sun Gwaka and Young-cheon Song* , Risk of Thromboembolism with the Angiogenesis inhibitor Bevacizumab in Metastatic Colo-Rectal Cancer Patients J. Kor. Soc. Health-Syst. Pharm., Vol. 28, No. 3, 279 ~ 287 (2011)

Young-Jong Lee, Ok-Sun Park, Yun-Hee Park, Jae-Yeon Kim, Young-Cheon Song*, and Hye-Sun Gwak, Analysis of risk factors affecting Cytomegalovirus infection according to medication uses after kidney transplantation. J. Kor. Soc. Health-Syst. Pharm., Vol. 28, No. 2, 153 ~ 160 (2011)

S.J. Seo, M.S. Kim, Y.J. Choi, H.Y. Shin, Y.C. Song*, Carboplatin hypersensitivity reactions in Korean patients with gynecologic cancers. J. Kor. Soc. Health-Syst. Pharm., Vol. 27, No. 4, 400 ~ 406 (2010)

Hyun-ae Choi, Ji-young Choi, Youn-hee Park, Jae-yeoun Kim, Young-cheon Song*, Hye-sun Gwaka, Analysis of Drug Interaction between Simvastatin and Cyclosporine J. Kor. Soc. Health-Syst. Pharm., Vol. 27, No. 3, 313 ~ 322 (2010)

Sun-young Shin, Seung-lan Kim, Yong-man Yoo, Hey-young Shin, Young-cheon Song* Improvement Activities for Appropriate Selection of Dosage Form of Drugs Administered via Enteral Feeding Tube. J. Kor. Soc. Health-Syst. Pharm., Vol. 27, No. 2, 159 ~ 166 (2010)
Jee-hye Jeong, Seong-gil Ryu, Jae-youn Kim, Hye-Sun Gwaka and Young-cheon Song*, Changes in blood concentrations of cyclosporine after combination with azoles in bone marrow transplant recipients J. Kor. Soc. Health-Syst. Pharm., Vol. 26, No. 4, 362 ~ 370 (2009)

Choi Ji young, Lee Ha young, Jung Eun Jung, Park Yun Hee, Han Hye Won, Kim Jae Yeun, Young-Cheon Song*, Physical Compatibility of a Gabexate with Selected Medications J. Kor. Soc. Health-Syst. Pharm., Vol. 27, No. 2, 110 ~ 118

경력

1993.3-2013.1 서울아산병원 약제팀
2007.1-2012.12 서울아산병원 약제팀장
2007 – 2010 한국병원약사회 총무이사
2011 – 2012 한국병원약사회 대의원회 부의장
2002.1-2003.12 약제정보 특수연구회 운영
2004.1-2012.12 한국병원약사회 약물경제성평가연구회 운영
2010 – 2012 대한약사회 임상약학 특별위원회 위원
2009 - 2012 송파구 약물오남용예방위원회 위원
2009 – 2012 한국병원약사회 전문약사 인증위원회 위원
2009 – 2012 한국보건사회약료경영학회 부회장
2013 – 현재 한국보건사회약료경영학회 병원약국경영관리 위원장
2013 – 현재 대한약물역학위해관리학회 기획이사
2012 – 현재 재단법인 병원약학교육연구원 이사
2013 – 현재 한국임상약학회 정회원 이사

수상경력
2006 식품의약품안전청장상
2010 복지부장관상

학력

1983년 (학사) 삼육대학교 약학
1985년 (석사) 성균관대학교 환경위생약학
1993년 (박사) 성균관대학교 환경위생약학

논문

[연구논문]

Tae Jin Kang‌, Sookyeon Lee‌, Rana P. Singh‌, Rajesh Agarwal‌ and Dongsool Yim, Anti-tumor activity of oxypeucedanin from Ostericum koreanum against human prostate carcinoma DU145 cells. Acta Oncol. 48(6) 895-900 (2009)

Sungsook Choi, Dongsool Yim and Sookyeon Lee, Radical Scavenging Activities and Protective Effects against Oxidative Damage to DNA of Extracts from Medicinal Plants with known Osteoprotective Effects. Kor. J. Pharmacogn., 40(2) 143-149 (2009)

Myungsook Choi, Dongsool Yim and Sookyeon Lee, Comparative Analysis on The Great Three Books of Oriental Medicines Kor. J. Pharmacogn.,39(4) 271-289 (2008)
Ji Young Choi, Ike Dela Pena, Jong Hyun Choi, Seo Young Yoon, Dongsool Yim, Yong Soo Lee, Kwang Ho Ko, Chan Young Shin, Jong Hoon Ryu, Won Ki Kim, and Jae Hoon Cheong, Psycholpharmacological Profile of the Water Extract of Gardenia jasminoides and Its Constituents Genipin and Geniposide, in Mice. Biomolecules & Therapeutics 16(2), 118-125 (2008)
Shinsuk Lee, Daehong Kim, Dongsool Yim, Sookyeon Lee Anti-inflammatory, Analgesic and Hepatoprotective Effect of Semen of Rumex crispus. Kor. J. Pharmacogn., 38(4) 334-338 (2007)

Jahoon Kang, Myung S. Choi, Sookyeon Lee and Dongsool Yim Anti-inflammatory, Analgesic and Hepatoprotective Effects of Aerial Part of Viburum sargentii for. sterile. Kor. J. Pharmacogn., 38(1) 22-26 (2007)

Jong Hyun Choi, Seo Young Yoon, Eun Joo Choi, Yim Sun Ryu, Hong Sook Ko, Dong Sool Yim, Youl Her. Yong Soo Lee, Mi Ryoung Song, and Cheong, J. H., Anxiotic and Antidepressant Activities of Ginsenoside Rb1. Journal Applied Pharmacology 15(1), 27-33 (2007)

Myung S. Choi, Dong S. Yim, and Sook Y. Lee. Bibliographical study on Oriental Medicines(II) Yakhak Hoeiji 51, 13-34 (2007)
Myung S. Choi, Dong S. Yim, and Sook Y. Lee. Bibliographical study on Sanghanron(I) Yakhak Hoeiji 50, 234-243 (2006)

Myung S. Choi, Dong S. Yim, and Sook Y. Lee. Bibliographical study on Sanghanron(II) The Journal of Sahm Yook University 39, 319-342 (2005)

Jahoon Kang, Sookyeon Lee and Dongsool Yim. Effect of isoimperatorin on the proliferation of prostate Cancer Cell line DU 145 cells. The Journal Applied Pharmacology 13(3) 185-189 (2005)

Hong S. Ko, Keum S. Lee, Blendyl S. Tan-Lee, Hyung K. Park, Gu Y. Yoo, Dong S. Yim, In K. Chung, Se K. Oh and Jae H. Cheong. Stress Related Activities of Gardenia jasmonoides : Comparative study with the of Red Ginseng. Yakhak Hoeiji 49(4) 291-298 (2005)

Ji H. Yun, Dong S. Yim, Jin Y. Kang, Byung Y. Kang, Eun a. Shin, Myung J. Chung, Soo D. Kim, Dae H. Baek, Kyung J. Kim and Nam J. Ha Identification of Lactobacillus ruminus SPM0211 Isolated from Healthy Koreans and Its Antimicrobial Activity against Some Pathogens. Arch Pharm Res 28(6), 660-666 (2005)

Rana P. Singh, Puja Agrawal, Dongsool, Yim, Chapla Agarwal, and Rajesh Agarwal. Acacetin inhibits cell growth and cell cycle progression, and induces apoptosis in human prostate cancer cells: structure-activity relationship with linarin and linarin acetate. Carcinogenesis 26(4), 845-854 (2005)

Dong S. Yim, Rana P. Singh, Chapla Agarwal, Sook Y. Lee, Hyung J. Chi and Rajesh Agarwal , A Novel Anticancer Agent, Decursin, Induces G1 Arrest and Apoptosis in Human Prostate Carcinoma DU145 Cells . Cancer Research, 65, 1035-1044 (2005)

Myung S. Choi, Dong S. Yim, and Sook Y. Lee. Bibliographical study on Sanghanron(I) The Journal of Sahm Yook University 39, (2004)

Sook Y. Lee, Kwang S. Kim, Dong S. Yim, Hepatoprotective activities of the processed roots of Rehmannia glutinosa. Jounal of Life Science 13, 55-66(2004)

Cheng, X. Z., Yim, D. S., Lee, S. Y., The Effect of Ka-Mi-Chung-Gan-Tang on Rat with Alcoholic Fatty Liver. Kor. J. Pharmacogn., 35 229-232(2004)

Yun, Y. H., Han, S. H., Park, E. J., Yim, D. S., See, S. Y., Lee, C. K., Cho, K. H.., Kim, K. J., Immunodulatory Activity of Betulinic Acidby Producing Pro-Inflammatory Cytokines and Activation of Macrophages. Arch. Pharm. Res, 26 1087-1095 (2003)

Han, S. H., Sung, K. H., Yim, D. S., Lee, S. Y., Cho, K. H., Lee, J. K., Ha, N. J.,Kim, K. J, Activation of Murine Macrophage Cellline Raw264.7 by Korean Propolis. Arch. Pharm.Res, 25 895-902 (2002)

Han, S. H., Sung, K. H., Yim, D. S., Lee, S. Y., Lee, C. K., Ha, N. J., and Kim, K. J., The effect of linarin on LPS-induced cytokine production and nitric oxide inhibition in murine macrophages cell line RAW264.7. Arch. Pharm.Res, 25 170-177 (2002)

Kim, Y.Y. , Lee, S.Y.and Yim, D.S. , Biological Activities of Linarin from Chrysanthemum zawadskii var. latilobum. Yakhak Hoiji, 45, 604-610(2001)

Park, H.S., Lee, C.J., Kim, B.K., Yim, D.S. and Cheong, J. H., Hair-Growth effect and single Dose Oral Toxicity Test of Illite Powder. The Journal of Applied Pharmacology, 9, 307-310 (2001)

Lee, S. S., Lee, S. Y., and Yim, D. S., Biological Activities of the semen of Rumex Crispus. Jounal of Life Science 8, 117-127 (2001)

Huf, Y. G., Yim, D. S. and Lee, S. Y. Biological activities of the Viburnum sargentii for. Sterile. Jounal of Life Science 8, 129-138(2001)

Kim, Y.Y. , Lee, S.Y. and Yim, D.S., Antipyretic, Antianalgesic, Anti-inflammatory Activities of herb of the Chrysanthemum zawadskii var. latilobum. Jounal of Life Science, 7, 47-58 (2000)

Yim, D. S. and Lee, S. Y. Biological Activities of the roots of Pseudostellaria heterophylla(II). Jounal of Life Science 7, 123-129 (2000)

[저서]

종합약용식물학: 임동술 외 18명, 학창사 (2000)
천연물화학: 임동술 외 27명, 영림사 (2003)
약사법규: 임동술 외 19명, 학창사 (2004)
보건복지교육II 임동술 외 삼육대학교 출판부 (2005)
생약학: 임동술 외 33명, 동명사 (2009)
약무관계법규I, II 임동술 외 19명, 학창사 (2010)

경력

1983. 9. ~ 1985. 2. 삼육대학교 약학과 조교
1985. 3. ~ 1988. 8. 삼육대학교 약학과 시간강사
1988. 9. ~ 1992. 2. 삼육대학교 중앙기기실 연구원
1992. 3. ~ 현재 삼육대학교 약학과 전임, 조교수, 부교수
1999. 3. ~ 2000. 2. 삼육대학교 약학과 학과장
2003. 1. ~ 2003.12. Univ. of Colorado(USA) 교환교수
2005년 3월 -2007년 2월 삼육대학교 대학원 약학과장
2007년 9월- 현재 삼육대학교 약학대학 학장

학력

1986년 (학사) 삼육대학교 약학과
1988년 (석사) 서울대학교 대학원 약학과
1995년 (박사) 서울대학교 대학원 약학과

논문

국제 전문학술지
1. Sung Sook Choi, Peter T. Chivers and Douglas E. Berg. 2011.Point mutations in Helicobacter pylori‘s fur regulatory gene that alter resistance to metronidazole, a prodrug activated by chemical reduction. PLoS ONE | www.plosone.org 1 March 2011 | Volume 6 | Issue 3 | e18236.
2. Hae Kyung Lee, Hyunjung Kim, Hiun Suk Chae, Sung Sook Choi, Hyung Keun Kim, Young Suk Cho, Lee So Maeng, Hee Na Kim and Kyu Heum Baik. 2011. Differences of Urease Activity and Expression of Associated Genes According to Gastric Topography. Helicobacter 16 (1), 20-26.
3. Sung Sook Choi, Hae Kyung Lee, and Hiun Suk Chae. 2010. In vitro photodynamic antimicrobial activity of methylene blue and endoscopic white light against Helicobacter pylori 26695. J. Photochem. Photobio. B. 101, 206–209.
4. Tobias D. Schoep, Alma Fulurija1, Fayth Good, Wei Lu1, Robyn P. Himbeck, Carola Schwan, Sung Sook Choi, Douglas E. Berg, Peer R.E. Mittl, Mohammed Benghezal and Barry J. Marshall. 2010. Surface Properties of Helicobacter pylori Urease Complex are Essential for Persistence. PLoS ONE | www.plosone.org 1 November 2010 | Volume 5 | Issue 11 | e15042.
5. Cathy M. Styer, Lori M. Hansen, Cara L. Cooke, Amy M. Gundersen, Sung Sook Choi, Douglas E. Berg,Mohammed Benghezal, Barry J. Marshall,Richard M. Peek, Jr, Thomas Bore´n, and Jay V. Solni. 2010. Expression of the BabA Adhesin During Experimental Infection with Helicobacter pylor. Infection and Immunity. 78 (4), 1593–1600.
6. Jung, Jae-Hyuk, Eun-Jeong Yoon, Eung-Chil Choi, and Sung-Sook Choi. 2009. Development of TaqMan Probe-Based Real-Time PCR Method for erm(A), erm(B), and erm(C), Rapid Detection of Macrolide-Lincosamide-Streptogramin B Resistance Genes, from Clinical Isolates. J. Micob. Biotech. 19(11),1464-1469.
7. Claudia Dumrese, Lutz Slomianka, Urs Ziegler, Sung Sook Choi, Awdhesh Kalia, Alma Fulurija, Wei Lu, Douglas E. Berg, Mohammed Benghezal, Barry Marshall, and Peer R.E. Mittl. 2009. The secreted Helicobacter cystein-rich protein A causes adherence of human monocytes and differentiation into a macrophage-like phenotype" FEBS Letters 583(10),1637-1643.

국내전문학술지
1. YuNa Park, JiHoon Kim and SungSook Choi.2011. The role of Helicobacter pylori‘s Fur protein in the oxidative stress induced by photodynamic therapy. Kor. J. Microbiol. 47(2), 124-129.
2. JiHoon Kim, MunJoo Ko, KaHee Kim, SeungHoon Lee, and Sung-Sook Choi. 2010. Antimicrobial Susceptibility of Staphylococci sp. Isolated from Bovine Milk. Kor. J. Microbiol. 46(4). 341-345.
3. HyeIn Lee, JaeHyuk Jung, SangJin Lee, and Sung-Sook Choi. 2010. Analysis of Genotype and Phenotype of Erythromycin Resistancein Enterococci spp. Isolated from Raw Milk Samples. Kor. J. Mocrobiol. 40(2), 148-151.
4. HyeIn Lee, SangJin Lee and Sung-Sook Choi. 2009. Antimicrobial Resistance Patterns of Enterococci spp. Isolated from RawMilk Samples. Journal of Food Hygiene and Safety 24(4), 373-377.
5. Sung-Sook Choi, DongSool Yim, and SookYeon Lee. 2009. Radical Scavenging Activities and Protective Effects against Oxidative Damage to DNA of Extracts from Medicinal Plants with known Ospeoprotective Effetcs. Kor. J. Pharmacogn 40(2) 143-149.
6. Jeong Jae Hyuk, Jeong SoonYoung, Lee SangJin and Choi SungSook. 2008. SYBR Green I-based real-time PCR assay and melting curve analysis for Rapid Detection of methicillin-resistance Staphylococcus aureus from raw milk samples. J. Food Hyg. Safety. 23(2),121-128.
7. Sung-Sook Choi. 2008. Transcriptional Regulatory Protein Fur of Helicobacter pylori and its role in Metronidazole Resistance. Yakhak Hoeji 52(3), 225-231.

경력

1995. 3-1997. 2 서울대학교 종합약학연구소 박사 후 연구원
1999. 3-2000. 8 삼육의명대학 전임강사
2000. 9-2005. 8 삼육의명대학 조교수
2005. 9-2006. 2 삼육의명대학 부교수
2006. 3-현재 삼육대학교 약학대학 약학과 부교수
2006.7-2007.7 Washington University in St. Louis, School of Medicine, Visiting Scholar
2011. 9-현재 삼육대학교 약학과 교수