학력

삼육대학교 약학과 졸업
경희대학교 대학원 약학대학 석사 졸업
경희대학교 대학원 약학대학 박사 졸업

논문

Controlled releas of silymarin from chitosan carrier, 한국 약제학회지, 1995. 3 호병균, 서성훈, 강진양

Controlled releas of piracetam with ion exchange resin, 한국 약제학회지, 1995. 6 강진양, 서성훈, 이경태

Development of stable magnesium citrate carthartic,한국 약제학회지, 1995. 10 이종석, 서성훈, 강진양

알긴산 비드를 이용한 하제의 연구,생명과학지(삼육대논문집), 3권, 1997. 3 강진양

Poly(D, L - lactic) acid를 이용한 Piracetam의 Microsphere 제조, 생명과학지(삼육대논문집), 4권, 1998. 2 강진양, 신길섭

약용탄 - Cataplasm의 제제화, 생명과학지(삼육대논문집), 4권, 1998. 2 강진양

약용탄 - Cataplasm의 제제화, 생명과학지(삼육대논문집), 4권, 1998. 2 강진양

Controlled releas and Bioavailability of Piraceta, 한국 약학회지 제 28권, 1998. 2 강진양, 서성훈, 이경태
프레드리솔론패취의 피부특성에 관한 실험, 생명과학지(삼육대학논문집), 5권, 1999. 2 강진양

황토파프 특허출원(1999. 12)

황토의 산화철(Fe2O3) 함량과 일반적 성질, 한국 약제학회지, 30권, 2000. 9 강진양, 김인규, 서성훈

섹심캅셀의 생물학적동등성시험, 화학요법지, 2000. 12 강진양, 서성훈, 강진한, 이경태

The Case-Control Studies Between The Single Nucleotide Polymorphisms of the Human SA and MTHFR Gene and Htpertension in Korean Population Environmental mutagens & calcinogens, 2002. 9. 26 강진양, 하남주, 강병룡

The Protein Polymorphism of Hapoglobin in Korean Elite Athletes Medical principle & practice, 2002. 12 강진양, 이강오, 강병룡

Muscle-Specific Creatine Kinase Gene Polymorphisms in Korean Elite Athletes, 한국독성학회, 2003. 6 강진양, 하남주, 최성숙

The Mitochondrial DNA 5178 A/C Polymorphism in Elite Korean Male Athletes Korean journal of genetics, 2003. 9. 30 강진양, 하남주, 강병룡

Association Study Between Genetic Polymorphisms in Inter lukin-1 Gene Family and Adult Periodontitis in Korean 한국독성학회, 2004. 12 강진양, 이강오, 강병룡

Identification of Lactobacillus ruminus SPM0211 Isolated from Healthy Koreans and Its Antimicrobial Activity against Some Pathogens, Archives of Pharmacal Research Vol.28, No.6, 대한약학회, 2005. 6. 30

Human G-protein B3 Subuit C825T Polymorphism is Associated with Serum Total Cholesterol and L D L -Cholesterol Levels in Koreans, Integrative Biosciences
Vol. 9, 한국동물학회, 2005. 7. 11

Safety Assessment of Potential Lactic Acid Bacteria Bifidobacterium longum SPM1205 Isolated from Healthy Koreans, The Journal of Microbiology Vol.43, No.6, The Microbiological Society of Korea, 2005. 7. 11

FAA와 HPMC을 위용한 Metformin HCI 함유 GR 타입 정제에 의한 용출을 개선,
약제학회지 제38권 제1호 51-55P, 한국약제학회, 2008. 2. 21

바클란정(바클로펜 10mg)에 대한 태평양바클로펜정의 생물학적동등성, Bioequivalence of Taepyungyang Baclofen Tablet to Baclan™ Table(Baclofen 10 mg), 약제학회지 제37권 제4호 249-254p, 한국약제학회, 2007. 6. 28

Effect of chromosomal variations on pharmacokinetic activity of zolpidem in healthy volunteer: An array-based comparative genomic hybridization study,
Biochemical and Biophysical Research Communications 356 981-987p,
Biochemical and Biophysical Research Communications, 2007. 3. 26

LC-MS/MS를 이용한 제일크라비트정(레보플록사신 100mg)에 대한 레사신정 100mg 의 생물학적 동등성, 약제학회지(2008) 제38권 제4호 pp.269~275, 한국약제학회, 2008. 9. 27

PEO와 HPMC를 이용한 티니다졸 정제의 용출율 개선, 약제학회지(2009) 제39권 제1호 pp.7~12, 한국약제학회, 2008. 12. 6

Development of Nifedipine-loaded Coated Gelatin Microcapsule as a Long Acting Or

경력

삼육대학교 약학과 교수
한국약제학학회 출판위원
삼육대학교 교무처장

학력

1992 삼육대학교 약학과 (약학)
1998 가톨릭대학교 대학원 의학과 (병리학)
2002 가톨릭대학교 대학원 의학과 (병리학) 의학박사
학위 논문 - 나병 병형에 따른 Toll-like receptor 2 의 역할

논문

Annamneedi VP, Park IH, Bae JP, Lee GS, Kang TJ. NLRP3 Inflammasome as Therapeutic Targets in Inflammatory Diseases. Biomol & Ther. 31(4): 395-401 (2023)
Annamneedi VP, Park JW, Lee GS, Kang TJ. Cell Autonomous Circadian Systems and Their Relation to Inflammation. Biomol & Ther. 29(1): 31-40 (2021)
Prakash AV, Park JW, Seong JW, Kang TJ. Repositioned Drugs for Inflammatory Diseases such as Sepsis, Asthma, and Atopic Dermatitis. Biomol & Ther. 28(3): 222-229 (2020)
Kim NY, Park K, Lee YJ, Kim YM, Hong SH, Son WR, Hong S, Lee S, Ahn HB, Yang J, Seo J, Lim Y, Yu CH, Hur GH, Jeong ST, Lee SH, Song K, Kang TJ, Shin YK, Choi J, Choi1 JY. Development of an Equine Antitoxin by Immunizing the Halla Horse with the Receptor-Binding Domain of Botulinum Neurotoxin Type A1 J. Microbiol. Biotechnol. 29(7), 1165–1176 (2019)
Kim SH, Lee KM, Lee GS, Seong JW, Kang TJ. Rifampicin alleviates atopic dermatitis-like response in vivo and in vitro. Biomol & Ther. 25(6): 634-640 (2017)
Choi JY, Shin S, Kim NY, Son WS, Kang TJ, Song DH, Yu CH, Hur GH, Jeong ST, Shin YK. A novel staphylococcal enterotoxin B subunit vaccine candidate elicits protective immune response in a mouse model. Toxicon. 131:68-77 (2017)
Joe HE, Choi JS, Park SG, Kang TJ, Kim JC, Shin YK. Identification of diagnostic biomarkers for early detection of anthrax from human aortic endothelial cells. Int. J. Nanotechnol. 13 (4-6): 413-425 (2016)
Kim TH, Chae GT, and Kang TJ. Expression of nucleotide-oligomerization domain(NOD) and related genes in mouse tissues infected with Mycobacterium leprae. Immune Netw. 15 (6): 319-324 (2015)
Lim SC, Lee KM, Kang TJ. Chitin from cuttlebone activates inflammatory cells to enhnace the cell migration. Biomol & Ther. 23 (4): 333-338 (2015)
Lee KM, Shim H, Lee GS, Park IH, Lee OS, Lim SC, Kang TJ. Chitin from the extract of cuttlebone induces acute inflammation and enhances MMP1 expressions. Biomol & Ther. 21 (3): 246-250 (2013)
Shim H, Moon JS, Lee SY, Yim DS, Kang TJ. Polyacetylene compound from Cirsium japonicum var. ussuriense inhibited caspase-1-mediated IL-1β expression Immune Network 12(5): 213-216 (2012)
Lee GS, Yim DS, Cheong JH, Kang TJ. The n-Hexane, ethylacetate, and butanol fractions from Hydnocarpi Semen enhanced wound healing in a mice ulcer model. Immunopharmacol. Immunotoxicol. 34 (6): 968-974 (2012)
Chung TH*, Kang TJ*, Cho W, Im GY, Lee GS, Yang MC, Cho C, Ma JY. Effectiveness of the Novel Herbal Medicine, KIOM-MA, and Its Bioconversion Product, KIOM-MA128, on the Treatment of Atopic Dermatitis. Evidence-Based Complementary and Alternative Medicine (eCAM) Volume 2012, Article ID 762918, 9 pages (Open Access Journal)
Kang TJ, Chae GT. The role of intracellular receptor NODs for cytokine production by macrophages infected with Mycobacterium leprae. Immune Network 11(6): 424-427 (2011)
Kang TJ. Moon JS, Lee SY, Yim DS. Polyacetylene compound from Cirsium japonicum var. ussuriense inhibited LPS-induced inflammatory reaction via suppression of NF-kB activity in RAW 264.cells Biomol & Ther. 19 (1): 97-101 (2011)
Kang TJ, Jin SH, Teum C, Lee SB, Kim CH, Lee SH, Kim KH, Shin E, Chae GT. Vitamin D receptor gne TaqI, Bsm I and FokI polymorphisms in Korean patients with Tuberculosis. Immune Network 11(5): 253-257 (2011)
Lee GS, Choi JY, Choi YJ, Yim DS, Kang TJ*, Cheong JH*, The wound healing effect of Hydnocarpi Semen extract on ulcer in diabetic mice. Biomol & Ther. 2010; 18 (3): 329-335 * Co-corresponding authors
Kang TJ, Lee GS, Kim SK, Jin SH, Chae GT, Comparison of Two Mice Strains, A/J and C57BL/6, in Caspase-1 Activity and IL-1β Secretion of Macrophage to Mycobacterium leprae Infection. Mediators of Inflammation, vol. 2010, Article ID 708713, 5 pages, 2010. doi:10.1155/2010/708713 (Open Journal)

경력

2007. 9 – 현재 삼육대학교 약학과 전임강사, 조교수, 부교수, 교수
2024. 3 – 현재 삼육대학교 약학대학 학장
2020. 2 - 2022. 1 삼육대학교 기획처장 & 대학혁신지원사업단장
2016. 6 - 2019. 2 삼육대학교 수도권특성화사업단(CK-II, 건강과학) 사업단장
2004. 8 - 2007. 7 미국 메릴랜드(주립) 의과대학 박사후 연구원
2003. 1 - 2003. 2 미국 네바다 주립대학 방문연구원
2002. 8 - 2004. 2 삼육간호보건대학 외래강사, 겸임교수
2002. 3 - 2004. 7 가톨릭의과대학 한센병연구소 박사후 연구원
2002. 3 - 2003. 12 삼육대학교 보건복지대학원 외래강사
2000. 3 - 2004. 6 삼육대학교 외래강사
1999. 3 - 1999. 6 서울보건대학 외래강사
1999. 3 - 2004. 7 가톨릭의과대학 병리학교실 연구조교
1993. 7 - 1996. 6 국군포항병원 약제과장
1992. 3 - 1992. 6 삼육대학교 약학과 조교

[학회 및 대외 활동]
2007. 1 - 현재 대한약학회 정회원 - (현)부회장 및 이사. (전)총무위원장, 재무위원장
2008. 1 - 현재 한국응용약물학회 정회원 - (현) 부회장, (전)사무총장, 총무위원장
2022. 2 – 현재 한국약학교육협의회 임원 - (현) 운영본부장 겸 총무위원장
2023. 1 – 현재 한국약학교육평가원 (현)인증관리위원장 (전)대외협력위원장
2024. 9 – 현재 식품의약품안전처 중앙약사심의위원회 위원
2023. 7 – 현재 한국보건의료인국가시험원 약사시험위원회 위원(간사)
2023. 7 – 현재 한국보건의료인국가시험원 약사 국가시험 임기제 시험위원
2013. 1 - 현재 한국분자세포생물학회 정회원
2008. 1 - 현재 대한면역학회 정회원
2006. 1 - 현재 생화학분자생물학회 정회원
2011. 8 - 2012. 12 Immune Network 편집위원

학력

2004 – 2008 학사, 삼육대학교, 약학과
2008 – 2010 약학 석사, 서울대학교, 약학대학
2010 – 2017 약학 박사, 서울대학교, 융합과학기술대학원, 분자 의약 및 바이오 제약학과

논문

1. Song Y, Kong H, Oh S, Kim SB*. Plant-derived extracellular vesicles as nanocarriers for combination therapy enhancing paclitaxel-based regimens in breast cancer. BMB Rep 2025;58:53-63.
2. Shin Y, Kim J, Song Y, Kim S, Kong H. Efficacy of laurus nobilis l. For tight junction protein imbalance in leaky gut syndrome. Nutrients 2024;16.
3. Lee W, Sohn E, Kim SB*. Myoblast-derived exosomes reduce anticancer drug-induced muscle toxicity via an autocrine pathway. Cell Mol Biol (Noisy-le-grand) 2024;70:103-109.
4. Lee H, Friedman MJ, Kim SB, Oh S. DNA regulatory element cooperation and competition in transcription. BMB Rep 2024;57:509-520.
5. Kim Y, Kim SB*, Lee H, Kim D, Bak SS, Yoon I, Cho S, Jeong SJ, Jeon Y, Kim J, et al. Aimp1-derived peptide secreted from hair follicle stem cells promotes hair growth by activating dermal papilla cells. Int J Biol Sci 2024;20:5764-5778.
6. Kim U, Hwang S, Cho S, Kim HY, Ban H, Park J, Mun J, Kim N, Suh JH, Choi J, et al. Intratumoral delivery of mrna encoding the endogenous tlr2/6 agonist une-c1 induces immunogenic cell death and enhances antitumor activity. Front Immunol 2024;15:1454504.
7. Kim J, An J, Song Y, Jang M, Kong H, Kim S. Effect of elderberry (sambucus nigra l.) extract intake on normalizing testosterone concentration in testosterone deficiency syndrome rat model through regulation of 17beta-hsd, 5alpha-reductase, and cyp19a1 expression. Nutrients 2024;16.
8. Kim J, An J, Lee YK, Ha G, Ban H, Kong H, Lee H, Song Y, Lee CK, Kim SB, et al. Hair growth promoting effects of solubilized sturgeon oil and its correlation with the gut microbiome. Pharmaceuticals (Basel) 2024;17.
9. Kim HY, Cho S, Kim SB, Song EC, Jung W, Shin YG, Suh JH, Choi J, Yoon I, Kim U, et al. Specific targeting of cancer vaccines to antigen-presenting cells via an endogenous tlr2/6 ligand derived from cysteinyl-trna synthetase 1. Mol Ther 2024;32:3597-3617.
10. Song EC, Park C, Shin Y, Kim WK, Kim SB, Cho S. Neurog1-derived peptides rmne1 and dualpep-shine penetrate the skin and inhibit melanin synthesis by regulating mitf transcription. Int J Mol Sci 2023;24.
11. Lim C, Lee S, Shin Y, Cho S, Park C, Shin Y, Song EC, Kim WK, Ham C, Kim SB, et al. Development and application of novel peptide-formulated nanoparticles for treatment of atopic dermatitis. J Mater Chem B 2023;11:10131-10146.
12. Kim S, Kim J, Song Y, Kim S, Kong H. Unripe rubus occidentalis, ellagic acid, and urolithin a attenuate inflammatory responses in il-1beta-stimulated a549 cells and pma-stimulated differentiated hl-60 cells. Nutrients 2023;15.
13. An J, Song Y, Kim S, Kong H, Kim K. Alteration of gut microbes in benign prostatic hyperplasia model and finasteride treatment model. Int J Mol Sci 2023;24.
14. Park MC, Goughnour PC, Jun S, Cho S, Song E, Kim SB, Kim HY, Hyun JK, Kim P, Jung HS, et al. Two distinct receptor-binding domains of human glycyl-trna synthetase 1 displayed on extracellular vesicles activate m1 polarization and phagocytic bridging of macrophages to cancer cells. Cancer Lett 2022;539:215698.
15. Lee H, An J, Kim J, Choi D, Song Y, Lee CK, Kong H, Kim SB, Kim K. A novel bacterium, butyricimonas virosa, preventing hfd-induced diabetes and metabolic disorders in mice via glp-1 receptor. Front Microbiol 2022;13:858192.
16. Kong H, Kim SB*. Exosomal communication between the tumor microenvironment and innate immunity and its therapeutic application. Immune Netw 2022;22:e38.
17. Kim SB. Function and therapeutic development of exosomes for cancer therapy. Arch Pharm Res 2022;45:295-308.
18. Yoon I, Nam M, Kim HK, Moon HS, Kim S, Jang J, Song JA, Jeong SJ, Kim SB, Cho S, et al. Glucose-dependent control of leucine metabolism by leucyl-trna synthetase 1. Science 2020;367:205-210.
19. Suh JH, Park MC, Goughnour PC, Min BS, Kim SB, Lee WY, Cho YB, Cheon JH, Lee KY, Nam DH, et al. Plasma lysyl-trna synthetase 1 (kars1) as a novel diagnostic and monitoring biomarker for colorectal cancer. J Clin Med 2020;9.
20. Goughnour PC, Park MC, Kim SB, Jun S, Yang WS, Chae S, Cho S, Song C, Lee JH, Hyun JK, et al. Extracellular vesicles derived from macrophages display glycyl-trna synthetase 1 and exhibit anti-cancer activity. J Extracell Vesicles 2020;10:e12029.
21. Cho S, Kim SB*, Lee Y, Song EC, Kim U, Kim HY, Suh JH, Goughnour PC, Kim Y, Yoon I, et al. Endogenous tlr2 ligand embedded in the catalytic region of human cysteinyl-trna synthetase 1. J Immunother Cancer 2020;8.
22. Kim SB*, Cho S, Kim S. Exosomal secretion of truncated cytosolic lysyl-trna synthetase induces inflammation during cell starvation. Cell Stress 2018;2:119-121.
23. Kim SB*, Kim HR, Park MC, Cho S, Goughnour PC, Han D, Yoon I, Kim Y, Kang T, Song E, et al. Caspase-8 controls the secretion of inflammatory lysyl-trna synthetase in exosomes from cancer cells. J Cell Biol 2017;216:2201-2216.

<도서>
1. 생화학 대한약학회 약품생화학 및 분자생물학분과 지음. 라이프사이언스 (2024)

<연구 과제>
2024 - 2025 ㈜CMC테크놀로지 연구 계약체결
2022 – 2023 한국연구재단 최초혁신실험실 과제 협약
2022 – 2027 한국연구재단 우수신진연구과제 협약
2021 – 2022 한국연구재단 기본연구과제 협약
2021 – 2022 ㈜메타포어, CML 진단키트 관련 연구 계약 체결
2021 – 2022 ㈜레메디 연구 계약체결

경력

2017 – 2019: 주임연구원, Cell bio 2 팀장, 서울대학교 (재) 의약바이오컨버젼스연구단
2019 – 2021: 선임연구원, Immuno Lab 팀장, (재)의약바이오컨버젼스연구단
2019 – 2020: ㈜ 자이메디 CEO
2020 – 현재: ㈜ 메타포어 (metapore) 바이오 자문위원
2021 – 현재: 삼육대학교 약학대학 조교수

<학회 및 대외 활동>
2025 – 현재 : 한국응용약물학회 정회원 – 현 홍보위원 (2025)
2021 – 현재 : 대한약학회 정회원. 현 총무위원(2025), 생화학분과 위원 (2023-2024)
2021 – 현재 : 생화학분자생물학회 정회원
2021 – 현재 : 한국세포생물학회 정회원

학력

1995.03 - 1999.02 삼육대학교 약학과[학사]
2001.09 - 2004.08 숙명여자대학교 임상약학대학원 임상약학 전공[석사]
2008.03 – 2010.08 숙명여자대학교 임상약학대학원 사회약학 전공[석사]
2011.09 – 2015.02 성균관대학교 약학대학 보건사회약학 전공[박사]

논문

• Jang SC, Kim GA, Lim YS, Kim HL, Lee EK. Association between everolimus combination therapy and cancer risk after liver transplantation: A nationwide population-based quasi-cohort study. Am J Transplant. 2025 Jan 16:S1600-6135(25)00005-X. doi: 10.1016/j.ajt.2025.01.005. Online ahead of print
• Park HY, Yoon EL, Kim M, Kwon SH, Kim D, Cheung R, Kim HL, Jun DW. Cost-effectiveness study of FIB-4 followed by transient elastography screening strategy for advanced hepatic fibrosis in a NAFLD at-risk population. Liver Int. 2024 Apr;44(4):944-954. doi: 10.1111/liv.15838.
• Park H, Yoon EL, Ito T, Jo AJ, Kim M, Lee J, Kim HL, Arai T, Atsukawa M, Kawanaka M, Toyoda H, Ishigami M, Yu ML, Jun DW, Nguyen MH. Diagnostic Performance of the Fibrosis-4 Index and Nonalcoholic Fatty Liver Disease Fibrosis Score in Lean Adults With Nonalcoholic Fatty Liver Disease. JAMA Netw Open. 2023 Aug 1;6(8):e2329568. doi: 10.1001/jamanetworkopen.2023.29568.
• Park HY, Kwon JW, Kim HL, Kwon SH, Nam JH, Min S, Oh IS, Bae S, Choi SH. Cost-Effectiveness of All-Oral Regimens for the Treatment of Multidrug-Resistant Tuberculosis in Korea: Comparison With Conventional Injectable-Containing Regimens. J Korean Med Sci. 2023 May 29;38(21):e167. Forthcoming. https://doi.org/10.3346/jkms.2023.38.e167
• Jang SC, Oh BC, Nam JH, Lee EK, Kim HL, Kwon SH. Clinical impact and economic burden of post-transplant infections following heart transplantation: A retrospective nationwide cohort study. J Heart Lung Transplant. 2022 Nov;41(11):1601-1610. doi: 10.1016/j.healun.2022.08.001.
• Kwon SH, Nam JH, Kim HL, Park HY, Kwon JW. Real-world association of adherence with outcomes and economic burden in patients with tuberculosis from South Korea claims data. Front Pharmacol. 2022 Aug 16;13:918344. doi: 10.3389/fphar.2022.918344. eCollection 2022.
• Jang SC, Nam JH, Lee SA, An D, Kim HL, Kwon SH, Lee EK. Clinical manifestation, economic burden, and mortality in patients with transthyretin cardiac amyloidosis. Orphanet J Rare Dis. 2022 Jul 15;17(1):262. doi: 10.1186/s13023-022-02425-3.
• Kim HL, Kim KA, Choi GH, Jang ES, Ki M, Choi HY, Jeong SH. A cost-effectiveness study of universal screening for hepatitis C virus infection in South Korea: A societal perspective. Clin Mol Hepatol. 2022 Jan;28(1):91-104. doi: 10.3350/cmh.2021.0236
• Cho JY, Kwon SH, Lee EK, Lee JH, Kim HL. Cost-Effectiveness of Adjuvant Immunotherapy With Cytokine-Induced Killer Cell for Hepatocellular Carcinoma Based on a Randomized Controlled Trial and Real-World Data. Front Oncol. 2021 Dec 3;11:728740. doi: 10.3389/fonc.2021.728740.
• Byun JY, Kim HL, Lee EK, Kwon SH. A Systematic Review of Economic Evaluations of Active Tuberculosis Treatments. Front Pharmacol. 2021 Dec 13;12:736986. doi: 10.3389/fphar.2021.736986
• Kim HL, Kim GA, Park JA, Kang HR, Lee EK, Lim YS. Cost-effectiveness of antiviral treatment in adult patients with immune-tolerant phase chronic hepatitis B. Gut. 2021;70:2172–2182.
doi:10.1136/gutjnl-2020-321309
• Kwon SH, Park HS, Na YJ, Park C, Shin JY, Kim HL. Price Reduction of Anticancer Drugs from 2007 to 2019 in South Korea: The Impact of Pharmaceutical Cost-Containment Policies. Appl
Health Econ Health Policy. 2021 May;19(3):439-450. doi: 10.1007/s40258-020-00604-6.

• 김진향, 김은석, 나홍주, 이유리, 이희조, 박일호, 양재욱, 김혜린. 국내 지역약국 약사의 약물관련문제에 관한 중재활동 현황. 약학회지. 2023. 67(2):128-136
• 이주현, 김혜린, 한혜성, 박일호, 손현순. 단골약국의 필요성과 단골약국에 기대하는 서비스. 약학회지. 2023. 37(1):58-65
• 박선경, 이주은, 김혜린, 최유정, 팽진철, 이승표. ATTR-CM 환자 진단에서 심내막 심근생검 대비 Nuclear Scintigraphy의 경제성분석연구 - Nuclear Scintigraphy의 비용-최소화분석. 보건의료기술평가. 2021. 9(2):108-114
• 오병찬, 조정연, 권순홍, 이의경, 김혜린. 환자표본자료를 이용한 간세포암종 환자의 의료이용 특성 및 치료별 의료비용 분석. 한국임상약학회지. 2021. 31(2):153-159
• 김혜린, 조윤희, 이정화, 전은용, 이주연, 김정미. 병원약사 약제서비스의 업무량 상대가치 조사. 병원약사회지. 2021. 38(2):155-170
• 김수진, 김혜린, 손현순. 외래환자의 약물요법 관련 전문직간 협업에 대한 의사와 약사의 인식. 약학회지. 2021. 65(2):158-167
• 권순홍, 손은혜, 김혜린. 우리나라와 일본의 지역약국 약사서비스 관련 공적보험급여의 범위 및 수가 비교. 약학회지. 2021. 65(1):10-16
• 김혜린, 김민혜, 박혜경. 우리나라와 일본의 병원약사와 관련된 업무에 대한 수가 비교. 병원약사회지. 2021. 38(1):75-92
• 김수정, 최나이, 임정미, 서성연, 조윤희, 조윤숙, 최유현, 박준동, 김혜린. 소아중환자실 담당약사의 병동상주 전후 임상적·경제적 효과 비교. 병원약사회지. 2020. 37(3):126-150
• 서성연, 김시형, 김성환, 김아정, 김현정, 배혜정, 신은정, 임정미, 장홍원, 최나이, 최정윤, 조윤희, 조은정, 조윤숙, 김혜린. 병원약사에 의해 수행되는 약제서비스의 현황 및 업무량 분석. 병원약사회지. 2020. 37(2):126-150

경력

2000.03 – 2003.03 서울대학교병원 약제부 약무직
2003.03 - 2010.10 분당서울대학교병원 약제부/물류자산팀 과장
2010.11 - 2012.02 숙명여자대학교 의약정보연구소 연구원
2012.02 - 2016.02 성균관대학교 약학연구원 선임연구원
2013.03 – 2015.12 삼육대학교 약학과 외래강사
2016.03 - 현재 삼육대학교 약학과 부교수

[학회 및 대외활동]
• 대학약학회 평생회원 (2018~현재)
• 질병관리본부 결핵 전문가 자문위원 (2019-2020)
• 삼육대학교 생명윤리위원회 위원/전문간사 (2020~2023)
• 서울대학교병원 약제부 자문교수 (2021~현재)
• 대학약학회 약학회지 편집간사 (2022~현재)
• 한국사회약학회(구.한국보건사회약료경영학회) 편집위원 (2022~현재)
• 한국약사커뮤티케이션학회 총무위원회 위원장/이사 (2022~2023)
• 한국의약품안전관리원 의약품부작용 전문위원회 전문위원 (2023-2024)
• 환자안전약물관리본부 지역의약품안전센터 평가자문위원회 위원 (2023-2024)

학력

1992. 2. 서울대학교 제약학과, 학사
1994. 2. 서울대학교 대학원 약학과, 약학석사 (약물학 전공)
2010. 8. 삼육대학교 대학원 약학과, 약학박사 (약물학 전공)

논문

1. Dooti Kundu, Srijan Acharya, Shujie Wang, Yongkai Cao, Hee Jin Kim,Jae Hoon Cheong, Kyeong-Man Kim (2024.11) Roles of metabotropic signaling of nicotine receptors in the development and maintenance of nicotine reward through regulation of dopamine D3 receptor expression. Journal of Neurochemistry. online
2. Hyeokjun Kwon, Eunchong Hong, Yong Sup Lee, Jae Hoon Cheong, Hee Jin Kim, Soyoung Kim, Jaesuk Yun (2024.07) Augmentation of intracranial self-stimulation induced by amphetamine-like drugs in Period circadian regulator 2 knockout mice is associated with intracellular Ca2+ levels. Neurosccience Research online
3. Leandro Val Sayson, Nicole Bon Campomayor, Darlene Mae Ortiz, Hyun Jun Lee, Sweetie Balataria, Sangsu Park, Jeongin Lim, Heejin Kang, Hee Jin Kim, Mikyung Kim (2024.09) Extracts of Prunella vulgaris Enhanced Pentobarbital-Induced Sleeping Behavior in Mice Potentially via Adenosine A2A Receptor Activity. Planta Med 90(11): 864-875
4. Leandro Val Sayson, Se Jin Jeon, Darlene Mae Ortiz, Hyun Jun Lee, Nicole Bon Campomayor, Hee Jin Kim, Mikyung Kim (2024.04) Heukharang (Lactuca sativa L.) extracts enhanced the sleep behavior of mice: potential involvement of adenosine A1 and A2A receptors. Sleep and Biological Rhythms 22(3): 385-394
5. Nicole Bon Campomayor; Hee Jin Kim; Hyun Jun Lee; Leandro Val Sayson; Darlene Mae D. Ortiz; Eunbi Cho; Dong Hyun Kim; Se Jin Jeon; Bung-Nyun Kim; Jae Hoon Cheong; Mikyung Kim (2024.07) Impact and Interrelationships of Striatal Proteins, EPHB2, OPRM1,and PER2 on Mild Cognitive Impairment. Molecular Neurobiology online
6. Hyun Jun Lee, Darlene Mae Ortiz, Leandro Val Sayson, Mikyung Kim, Jae Hoon Cheong, Hee Jin Kim (2024.01) Ameliorating Effects of Acanthopanax Koreaum Extract and Components on Nicotine Dependence and Withdrawal Symptoms via the DRD1-EPAC-ERK-CREB Pathway. Addiction Biology 29(2): e13360
7. Raly James Perez Custodio, Jan G Hengstler, Jae Hoon Cheong, Hee Jin Kim, Edmund Wascher, Stephan Getzmann (2023.10) Adult ADHD: it is old and new at the same time - what is it. Reviews in the Neurosciences 35(2): 225-241
8. Darlene Mae D. Ortiz1, Hyeyeon Oh2, Soonyong Kwon2, Eunseon Jeon2, Muhammad Kamal Hossain3, Hee Jin Kim1,*, and Mikyung Kim (2023.09) Sleep-potentiating Effects of Passiflora incarnata and ‘Heukharang’, a Novel Korean Lactuca sativa, on Pentobarbital-induced Sleep in Mice. Natural Product Sciences 29(3): 138-145
9. Leandro Val Sayson a, Hyun Jun Lee a, Darlene Mae Ortiz a, Mikyung Kim b, Raly James Perez Custodio c, Chae Hyeon Lee d, Yong Sup Lee d, Jae Hoon Cheong e, Hee Jin Kim (2023.08) The differential vulnerabilities of Per2 knockout mice to the addictive properties of methamphetamine and cocaine. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 126: 110782
10. Raly James Perez Custodio, Darlene Mae Ortiz, Hyun Jun Lee, Danilo Buctot, Leandro Val Sayson, Mikyung Kim, Yong Sup Lee, Kyeong-Man Kim, Jae Hoon Cheong, and Hee Jin Kim (2023.10) Serotonin 2C receptors are also important in head twitch responses in male mice. Psychopharmacology. online publish
11. Ahn , Sungjin ; Ahn, Myunghwan; Park, Suzie; An, Seungchan; Park, Inguk; Hwang, Seok Young; Gong, Junpyo; Oh, Soyeon; Jin, Sun Hee ; Kim, Hee Jin; Cheong, Jae Hoon; Byun, Youngjoo; Noh, Minsoo (2023.01) Discovery of PPARγ and Glucocorticoid Receptor Dual Agonists to Promote the Adiponectin and Leptin Biosynthesis in Human Bone Marrow Mesenchymal Stem Cells. European Journal of Medicinal Chemistry 245(Pt1): 114927
12. Hee Jin Kim, Min Yeong Lee, Gyu Ri Kim, Hyun Jun Lee, Leandro Val Sayson, Darlene Mae D. Ortiz, Jae Hoon Cheong, Mikyung Kim (2023.07) Korean red ginseng extract attenuates alcohol-induced addictive responses and cognitive impairments by alleviating neuroinflammation. Journal of Ginseng Research 47(4): 583-592
13. Leandro Val Sayson, Darlene Mae Ortiz, Hyun Jun Lee, Mikyung Kim, Raly James Perez Custodio, Jaesuk Yun, Chae Hyeon Lee, Yong Sup Lee, Hye Jin Cha, Jae Hoon Cheong and Hee Jin Kim (2023) Deletion of Cryab increases the vulnerability of mice to the addiction-like effects of the cannabinoid JWH-018 via upregulation of striatal NF-κB expression. Frontiers in Pharmacology 14: 1135929
14. Darlene Mae D. Ortiz, Mikyung Kim, Hyun Jun Lee, Crislean Jun Botanas, Raly James Perez Custodio, Leandro Val Sayson, Nicole Bon Campomayor, Yong sup Lee, Jae Hoon Cheong, and Hee-Jin Kim (2023) 4-F-PCP, a Novel PCP Analog Ameliorates the Depressive-Like Behavior of Chronic Social Defeat Stress Mice via NMDA Receptor Antagonism. Biomolecues & Therapeutics 31(2): 227-239
15. Raly James Perez Custodio, Mikyung Kim, Young-Chul Chung, Bung-Nyun Kim, Hee Jin Kim, and Jae Hoon Cheong (2023) Thrsp Gene and the ADHD Predominantly Inattentive Presentation. ACS Chemical Neuroscience 14(4): 573-589
16. Raly James Perez Custodio, Hee Jin Kim, Jiyeon Kim, Darlene Mae Ortiz, Mikyung Kim, Danilo Buctot, Leandro Val Sayson, Hyun Jun Lee, Bung-Nyun Kim, Eugene C. Yi, and Jae Hoon Cheong (2023) Hippocampal dentate gyri proteomics reveals Wnt signaling involvement in the behavioral impairment in the THRSP-overexpressing ADHD mouse model. Communications Biology 6(1): 55
17. Keremkleroo Jym Adil 1, Chilly Gay Remonde 1, Edson Luck Gonzales 1, Kyung-Jun Boo 1, Kyong Ja Kwon 1, Dong Hyun Kim 1, Hee Jin Kim 2, Jae Hoon Cheong 3, Chan Young Shin 1, Se Jin Jeon (2022.07) Behavioral Deficits in Adolescent Mice after Sub-Chronic Administration of NMDA during Early Stage of Postnatal Development. Biomolecules & Therapeutics 30(4): 320-327
18. Ryeong-Eun Kim, Darine Froy Mabunga, Hee Jin Kim, Seol-Heui Han, Hahn Young Kim, Chan Young Shin and Kyoung Ja Kwon (2022.11) Novel Therapeutics for Treating Sleep Disorders: New Perspectives on Maydis stigma. Int J Molecular Sciences 23(23): 14612
19. Hyun Jun Lee, Sang Back Kim, Kyung Jun Boo, Darlene Mae Ortiz, Leandro Val Sayson, Raly James Perez Custodio, Jae Hoon Cheong, Seul Ki Kim, Mikyung Kim1,6,*, and Hee Jin Kim (2022.06) Standardized extract (HemoHIM) ameliorated high intensity exercise induced fatigue in mice. Natural Product Sciences 28(2): 68-74
20. Raly James Perez Custodio, Mikyung Kim, Leandro Val Sayson, Darlene Mae Ortiz, Danilo Buctot, Hyun Jun Lee, Jae Hoon Cheong, and Hee Jin Kim (2022.07) Regulation of clock and clock-controlled genes during morphine reward and reinforcement: Involvement of the period 2 circadian clock. Journal of Psychopharmacology 36(7): 875-891
21. Mikyung Kim · Raly James Custodio · Hyun Jun Lee · Leandro Val Sayson · Darlene Mae Ortiz ·Bung Nyun Kim · Hee Jin Kim · Jae Hoon Cheong (2022.07) Per2 Expression Regulates the Spatial Working Memory of Mice through DRD1 PKA CREB Signaling. Molecular Neurobiology 59(7): 4292-4303
22. Leandro Val Sayson, Mikyung Kim, Se Jin Jeon, Raly James Perez Custodio, Hyun Jun Lee, Darlene Mae Ortiz, Jae Hoon Cheong, and Hee Jin Kim (2022.05) Differentially expressed genes in Period 2-overexpressing mice striatum may underlie their lower sensitivity to methamphetamine addiction-like behavior. Biomolecules & Therapeutics 30(3): 238-245
23. Tae-Ho Kim, Katrina Joy Bormate, Raly James Perez Custodio, Jae Hoon Cheong, Bo Kyung Lee, Hee Jin Kim , Yi-Sook Jung (2022.01) Involvement of the adenosine A1 receptor in the hypnotic effect of rosmarinic acid. Biomedicine & Pharmacotherapy 146: 112483
24. Raly James Perez Custodio, Mikyung Kim, Leandro Val Sayson, Hyun Jun Lee, Darlene Mae Ortiz, Bung Nyun Kim, Hee Jin Kim* and Jae Hoon Cheong (2021.09) Low striatal T3 is implicated in inattention and memory impairment in an ADHD model overexpressing thyroid hormone-responsive protein. Communication Biology 4(1): 1101
25. Kun Won Lee, Ahmed H.E. Hassan, Youngdo Jeong, Seolmin Yoon, Seung-Hwan Kim, Cheol Jung Lee, Hye Rim Jeon, Suk Woo Chang, Ji-Young Kim, Dae Sik Jang, Hee Jin Kim, Jae Hoon Cheong and Yong Sup Lee (2021.01) Enantiopure methoxetamine stereoisomers: Chiral resolution, conformational analysis, UV-circular dichroism spectroscopy and electronic circular dichroism. New J Chem 45: 4354-4364
26. Daehyun Kim , Byounggwan Lee , Heejin Kim , Mikyung Kim (2021.06) Effects of Red Ginseng on Exercise Capacity and Peripheral Fatigue in Mice. Physical Therapy Rehabilitation Science. 10(2): 175-184
27. Donghyun Park, Darine Froy N. Mabunga,Keremkleroo Jym Adil, Onjeon Ryu, Schley Valencia, Ryeongeun Kim, Hee Jin Kim, Jae Hoon Cheong, Kyung Ja Kwon, Hahn Young Kim, Seol-Heui Han, Se Jin Jeon, Chan Young Shin (2021.04) Synergistic efficacy and diminished adverse effect profile of composite treatment of several ADHD medications. Neuropharmacology 187: 108494
28. Chrislean Jun Botanas, Raly James Custodio, Hee Jin Kim, June Bryande la Pena, Leandro Val Sayson, Darlene Mae Ortiz, Mikyung Kim, Hyun Jun Lee, Srijan Achary, Kyeong-Man Kim, Cheol Jung Lee, Jong Hoon Ryu, Yong Sup Lee, Jae Hoon Cheong (2021.08) R (−)-methoxetamine exerts rapid and sustained antidepressant effects and fewer behavioral side effects relative to S (+)-methoxetamine. Neuropharmacology 193: 108619
29. Arvie Abiero, Raly James Perez Custodio, Chrislean Jun Botanas, Darlene Mae Ortiz, Leandro Val Sayson, Mikyung Kim, Hyun Jun Lee, Seolmin Yoon, Yong Sup Lee, Jae Hoon Cheong, and Hee Jin Kim (2021.03) 1-phenylcyclohexan-1-amine hydrochloride (PCA HCl) alters mesolimbic dopamine system accompanied by neuroplastic changes: A neuropsychopharmacological evaluation in rodents. Neurochem Intern 144: 104962
30. Mikyung Kim, Sejin Jeon, Raly James Custodio, Hyun Jun Lee, Leandro Val Sayson, Darlene Mae Ortiz, Jae Hoon Cheong, and Hee Jin Kim (2021.03) Gene expression profiling in the striatum of Per2 KO mice which showed more vulnerable responses against methamphetamine. Biomol Ther 29(2): 135-143
31. Darlene Mae Ortiz, Raly James Custodio, Chrislean Jun Botanas, Leandro Val Sayson, Mikyung Kim, Hyun Jun Lee, Hee Jin Kim, Youngdo Jeong, Sulmin Yoon, Yong Sup Lee and Jae Hoon Cheong (2021.07) The dopaminergic alterations induced by 4-F-PCP and 4-Keto-PCP may enhance their drug-induced rewarding and reinforcing effects: Implications for abuse. Addiction Biology 26(4): e12981

특허
1. [Thrsp 과발현 형질전환 동물모델 및 이의 용도] 발명인: 정재훈, 김희진, 김붕년, 류재웅 출원인: 삼육대학교산학협력단 출원번호 10-2017-0025742 출원일 2017.02.27. 등록번호 10-1917346 등록일 2018.11.05.
2. [신규 케타민 유도체 및 이의 우울증의 예방 또는 치료용도] 발명인 정재훈, 이용섭, 김희진, 출원인 삼육대학교산학협력단 , 경희대학교 산학협력단, 출원번호 10-2018-0044187, 출원일 2018.04.17., 등록번호 10-2104953, 등록일 2020.04.21.
3. [지황추출물을 유효성분으로 포함하는 틱 장애의 예방 또는 치료용 조성물] 발명인 정재훈, 김희진, 김미경, 출원인 삼육대학교 산학협력단, 출원번호 10-2020-0009819, 출원일 2020.01.28. 등록번호 10-2338347 등록일 2021.12.07.
4. [신이 추출물 또는 분획물을 포함하는 수면 유도 및 개선용 조성물] 발명인 정재훈, 김희진, 유경이, 출원인 삼육대학교 산학협력단, 출원번호 10-2020-0002403, 출원일 2020.01.08. 등록번호 10-2287719, 등록일 2021.08.03.
5. [섬오갈피 추출물을 포함하는 니코틴 중독 및 금단증상의 예방 또는 치료용 조성물] 발명인 정재훈, 김희진, 이현준, 출원인 삼육대학교 산학협력단, 출원번호 10-2020-0019403, 출원일 2020.02.18. 등록번호 10-2415268, 등록일 2022.06.30.
6. [마약류 평가용 동물모델 및 이를 이용한 마약류 의존성 평가 방법] 발명인 김희진 이현준 쿠스토디오 랠리제임스 세이손 린드로발 오르티즈 달린메 정재훈 윤재석, 출원인 삼육대, 충북대, 전북대, 식약처, 출원번호 10-2022-0092173, 출원일 2022.07.26.
7. [시린진을 포함하는 니코틴 중독 및 금단 증상의 예방, 개선 또는 치료용 조성물] 발명인 김희진 김미경 이현준 정재훈, 출원인: 삼육대산단, 전북대산단, 출원번호 10-2022-0100702, 출원일 2022.08.113
8. [클로로젠산을 포함하는 니코틴 중독 및 금단 증상의 예방, 개선 또는 치료용 조성물] 발명인 김희진 김미경 이현준 정재훈, 출원인: 삼육대산단, 전북대산단, 출원번호 10-2022-0100712, 출원일 2022.08.11.
9. [자폐 스펙트럼 장애 진단용 조성물, 키트 및 방법] 발명인 이유진, 조아라, 김지연, 김붕년, 정재훈, 김희진, 출원인 서울대산단, 서울대병원산단, 삼육대산단, 전북대산단, 출원번호 10-2023-0122635, 출원일 2023.09.14

경력

1994.01 – 1997.04 LG 화학 기술연구원, 연구원
1997.05 – 2002. 07 LG생명과학, 학술 및 마케팅 과장
2016.06 –현재 삼육대학교 약학대학 조교수, 부교수

학력

1999. 2. 서울대학교 약학과, 약학사
2001. 2. 서울대학교 약학과, 약학석사
2007. 8. 서울대학교 약학과, 약학박사

논문

1. Minecoside promotes apoptotic progression through STAT3 inactivation in breast cancer cells. Oncol Lett. 2022 Mar;23(3):94. Buyun Kim, Ki Yong Lee, Byoungduck Park* (IF : 2.5)
2. PBN inhibits a detrimental effect of methamphetamine on brain endothelial cells by alleviating the generation of reactive oxygen species. Arch Pharm Res. 2020 Dec;43(12):1347-1355. Jong Su Hwang, Eun Hye Cha, Byoungduck Park, Eunyoung Ha, Ji Hae Seo (IF : 6.9)
3. Characterization and Optimization of the Tyrosinase Inhibitory Activity of Vitis amurensis Root Using LC-Q-TOF-MS Coupled with a Bioassay and Response Surface Methodology. Molecules. 2021 Jan 16;26(2):446. Kyung-Eon Oh, Hyeji Shin, Mi Kyeong Lee, Byoungduck Park*, Ki Yong Lee* (IF : 4.2)
4. Isoorientin Inhibits Amyloid β25-35-Induced Neuronal Inflammation in BV2 Cells by Blocking the NF-κB Signaling Pathway. Molecules. 2021 Nov 22;26(22):7056. Buyun Kim, Ki Yong Lee*, Byoungduck Park* (IF : 4.2)
5. Icariin sensitizes human colon cancer cells to TRAIL‑induced apoptosis via ERK‑mediated upregulation of death receptors. Int J Oncol. 2020 Mar;56(3):821-834. Buyun Kim, Ji Hae Seo, Ki Yong Lee*, Byoungduck Park* (IF : 5.65)
6. Characterization of Anti-Inflammatory and Antioxidant Constituents from Scutellaria baicalensis Using LC-MS Coupled with a Bioassay Method. Molecules. 2020 Aug 9;25(16):3617 Yoo Kyong Han, Hyunwoo Kim, Hyeji Shin, Jiyeon Song, Mi Kyeong Lee, Byoungduck Park*, Ki Yong Lee (IF : 4.411)
7. Methamphetamine-Induced Neuronal Damage: Neurotoxicity and Neuroinflammation.
Biomol Ther (Seoul). 2020 Sep 1;28(5):381-388. Buyun Kim, Jangmi Yun, Byoungduck Park* (IF : 4.634)
8. MeBib Suppressed Methamphetamine Self-Administration Response via Inhibition of BDNF/ERK/CREB Signal Pathway in the Hippocampus. Biomol Ther (Seoul). 2020 Nov 1;28(6):519-526. Buyun Kim, Sonam Jha, Ji Hae Seo, Chul-Ho Jeong, Sooyeun Lee, Sangkil Lee, Young Ho Seo, Byoungduck Park* (IF : 4.634)
9. In vitro synergistic effect of retapamulin with erythromycin and quinupristin against Enterococcus faecalis. J Antibiot (Tokyo). 2020 Sep;73(9):630-635. Byoungduck Park, Yu-Hong Min (IF : 2.649)
10. Minecoside Modulates Cell Invasion via Regulation of CXCR4 Expression in Breast and Colon Cancer Cells. Planta Med. 2020 Mar;86(5):331-337. Buyun Kim, Yu-Hong Min, Byoungduck Park* (IF : 3.352)
11. Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of T reg Cells. Cell Rep. 2019 Jun 4;27(10):2948-2961.e7. Maheshwor Timilshina, Zhiwei You, Sonja M Lacher, Suman Acharya, Liyuan Jiang, Youra Kang, Jung-Ae Kim, Hyeun Wook Chang, Keuk-Jun Kim, Byoungduck Park, Jae-Hyoung Song, Hyun-Jeong Ko, Yun-Yong Park, Min-Jung Ma, Mahesh Raj Nepal, Tae Cheon Jeong, Yeonseok Chung, Ari Waisman, Jae-Hoon Chang (IF : 9.423)
12. Epicatechin Prevents Methamphetamine-Induced Neuronal Cell Death via Inhibition of ER Stress. Biomol Ther (Seoul). 2019 Mar 1;27(2):145-151. Youra Kang, Ji-Ha Lee, Young Ho Seo, Jung-Hee Jang, Chul-Ho Jeong, Sooyeun Lee, Gil-Saeng Jeong, Byoungduck Park* (IF : 4.634)
13. Neotuberostemonine inhibits osteoclastogenesis via blockade of NF-κB pathway. Biochimie. 2019 Feb;157:81-91. Jangmi Yun, Ki Yong Lee, Byoungduck Park* (IF : 4.079)

경력

2007. 10. – 2009. 2. 서울대학교 약학대학 연수연구원
2009. 3. – 2009. 6. 고려대학교 생명공학원 연구교수
2009. 8. – 2011.12. University of Texas, MD Anderson Cancer Center 박사 후 연구원
2012. 3. – 2024. 2. 계명대학교 약학대학 부교수
2024. 3. – 현재 삼육대학교 약학대학 부교수

학력

1993. 2. 삼육대학교 약학과, 약학사
1995. 2. 서울대학교 약학과, 약학석사
2002. 2. 서울대학교 약학과, 약학박사

논문

1. Characterization of polymorphisms in IL-6 and PPAR-γ2 genes of elite college throwers. J. Converg. Sports. Exerc. Sci. 2023 Mar;21(1): 37-48. Il-Ho Park, Jae-Koo Lee
2. The genetic screening test using three SNPs to explore useful genetic markers influencing athletic performance of throwing discipline. J. next-generation Converg. Tech. Association. 2023 May;7(5): 811-822. Il-Ho Park, Jae-Koo Lee
3. Elucidation of Phytochemicals Affecting Platelet Responsiveness in Dangguisu-san: Active Ingredient Prediction and Experimental Research Using Network Pharmacology. Plants. 2023 Mar;12(5):1120. Dong-Ha Lee, Hee Jae Kwak, Yonghee Shin, Sung Jin Kim, Ga Hee Lee, Il-Ho Park, Seung Hyun Kim, Ki Sung Kang
4. Gintonin Isolated from Ginseng Inhibits the Epithelial—Mesenchymal Transition Induced by TGF-β in A549 Lung Cancer Cells. Plants. 2023 May; 12(10):2013. Sung Jin Kim, Seung-Yeol Nah, Il-Ho Park, Myoung-Sook Shin, Ki Sung Kang
5. Laricitrin 3-rutinoside from Ginkgo biloba fruits prevents damage in TNF-α-stimulated normal human dermal fibroblasts. Antioxidants. 2023 Jul;12(7):1432, Sullim Lee,Yea Jung Choi, Chen Huo, Akida Alishir, Ki Sung Kang, Il-Ho Park, Taesu Jang, Ki Hyun Kim
6. NLRP3 inflammasome as therapeutic targets in inflammatory diseases. Biomolecules & Therapeutics. 2023 Jul;31(4):395-401. Annamneedi Venkata Prakash, Il-Ho Park, Jun Woo Park, Jae Pil Bae, Geum Seon Lee, Tae Jin Kang
7. Development of fixed-dose combination with dual-release properties using double-melt extrusion technology. J. Drug Deliv. Sci. Technol. 2023 Sep; 87: 104809. Hee-Kyung Seo, Chulhun Park, Hye-Sung Oh, Il-Ho Park, Chin-Yang Kang, Beom-Jin Lee, Ike de la Pena, Kwon-Yeon Weon, Jun-Bom Park

경력

2002. 6. – 2004. 2. Suntory Bioorganic Research Institute, Japan 박사 후 연구원
2008. 7. – 2009. 7. University of California, Riverside 연구교수
2004. 3. – 현재 삼육대학교 약학대학 부교수

학력

1995.03~1999.02 삼육대학교, 약학과, 학사
1999.03~2001.02 삼육대학교 대학원 약학과, 석사
2008.03~2012.08 강원대학교 약학과, 박사

논문

PUBLICATIONs
Chulhun Park, Vanamane S. Renuka, Beom-Jin Lee, Ike de la Peña and Jun-Bom Park, Advancements of Hot-Melt Extrusion Technology to Address Unmet Patient Needs and Pharmaceutical Quality Aspects, Journal of Pharmaceutical Investigation, 2025, online

Hye-Sung Oh and Jun-Bom Park, Development of 3D-printed dual-release fixed-dosed combination through double-melt extrusion, International Journal of Pharmaceutics, 2024, 661, 124407

Se Jung Hwang, Jeong Hyeon Lee, Ji Hoon Choi1, Gi-Su Oh, Hong-Seob So, Jun-Bom Park, Kwon Yeon Weon, Development of a self-microemulsifying drug delivery system using a Dunnione to enhance bioavailability, Journal of Pharmaceutical Investigation, 2024, 54(5), 605-615

Sung-Yeop Kim, Ike de la Pena, Kwon Yeon Weon & Jun-Bom Park, Preparation of tofacitinib sustained-release tablets using hot melt extrusion technology, Pharmaceutical Development and Technology, 2024, 29(3), 248-257

Woojun Kim, Hai V. Ngo, Hy D. Nguyen, Ji-Min Park, Kye Wan Lee, Chulhun Park, Jun-Bom Park and Beom-Jin Lee, Nanonization and Deformable Behavior of Fattigated Peptide Drug in Mucoadhesive Buccal Films, Pharmaceutics, 2024, 16,486

Ju-Hyeong Woo, Hai V. Ngo, Hy D. Nguyen, Myung-Chul Gil, Chulhun Park, Jun-Bom Park, Jing-Hao Cui, Qing-Ri Cao, Beom-Jin Lee, Polyelectrolyte-based solid dispersions for enhanced dissolution and pH-Independent controlled release of sildenafil citrate, Heliyon 2023, 9, e23091

Hoyoung Kim, Eun-Ji Kim, Hai V. Ngo, Hy D. Nguyen, Chulhun Park, Kyung Hyun Choi, Jun-Bom Park and Beom-Jin Lee, Cellular Efficacy of Fattigated Nanoparticles and Real-Time ROS Occurrence Using Microfluidic Hepatocarcinoma Chip System: Effect of Anticancer Drug Solubility and Shear Stress, Pharmaceuticals 2023, 16, 1330. https://doi.org/10.3390/ph16091330

Hee-Kyung Seo, Chulhun Park, Hye-Sung Oh, Il-Ho Park, Chin-Yang Kang, Beom-Jin Lee, Ike de la Pena, Kwon-Yeon Weon, Jun-Bom Park, Development of fixed-dose combination with dual-release properties using double-melt extrusion technology, Journal of Drug Delivery Science and Technology, 2023, 87, 104809

Ju-Hyun Lee, Chulhun Park, In-OK Song, Beom-Jin Lee, Chin-Yang Kang and Jun-Bom Park, Investigation of Patient-Centric 3D-Printed Orodispersible Films Containing Amorphous Aripiprazole, Pharmaceuticals, 2022, 15, 895. https://doi.org/10.3390/ph15070895

Ju-Hyun Lee , Chulhun Park , Kwon-Yeon Weon, Chin-Yang Kang, Beom-Jin Lee and Jun-Bom Park, Improved Bioavailability of Poorly Water-Soluble Drug by Targeting Increased Absorption through Solubility Enhancement and Precipitation Inhibition, Pharmaceuticals, 2021, 14,1255. https://doi.org/10.3390/ph14121255

Hyungtaek Kim, Dahee Song, Hai V. Ngo, Gang Jin, Chulhun Park, Jun-Bom Park, Beom-Jin Lee, Modulation of the clinically accessible gelation time using glucono-d-lactone and pyridoxal 5′-phosphate for long-acting alginate in situ forming gel injectable, Carbohydrate Polymers, 2021, 272, 118453

Juhyun Lee, Hai V. Ngo, Gang Jin, Chulhun Park, Jun-Bom Park, Phuong H.L. Tran, Thao T.D. Tran, Van Hong Nguyen, Beom-Jin Lee, Effect of pH adjustment and ratio of oppositely charged polymers on the mechanistic performance and sustained release of volatile perfume in interpo- lyelectrolyte complex microcapsules, International Journal of Pharmaceutics, 2021, 604, 120672

Ji Yeon Park, Dong Ho Oh, Sang-Wook Park, Bo Ram Chae, Chul Woo Kim, Sang Heon Han, Hyeon Jong Shin, Soo Bin Yeom, Da Yeong Lee, Min Kyu Park, Sang-Eun Park, Jun-Bom Park* and Kyung-Tae Lee*, Development of Pelubiprofen Tromethamine with Improved Gastrointestinal Safety and Absorption, Pharmaceutics, 2021, 13,745

Yu-Byoung Chae, Sung-Yeop Kim, Chin-Yang Kang, and Jun-Bom Park, Effect of Hydrophilic and Hydrophobic Polymers on the Sustained-release Sarpogrelate HCl from Matrix Tablets, J. Pharm. Soc. Korea 2020, 64(6), 446-453

Hee Jo Yoo, Se-Jung Hwang, Jeong-Hun Lee, Wang-Seo Shim, Yun-Woong Choi, Sang Min Cho, Eun Kyoung Chung*, Jun-Bom Park*, Kyung-Tae Lee*, Development and Validation of an LC-MS/MS Assay to Quantitate 2′,4′,6′-Trihydroxyacetophenone in Rat and Dog Plasma and its Application to a Pharmacokinetic Study, Molecules 2020, 25, 4373

Sung-Min Choi, Sung-Hoon Lee, Chin-Yang Kang and Jun-Bom Park, Preparation of Hot-Melt Extruded Dosage Form for Enhancing Drugs Absorption Based on Computational Simulation, Pharmaceutics, 2020, 12, 757

Byung-Cheol Oh, Gang Jin, Chulhun Park, Jun-Bom Park, Beom-Jin Lee, Preparation and evaluation of identifiable quick response (QR)-coded orodispersible films using 3D printer with directly feeding nozzle, International Journal of Pharmaceutics, 2020, 584, 119405

Ilhwan Hwang, Vanamane Renuka, Ju-Hyun Lee, Kwon-Yeon Weon, Chin-Yang Kang, Beom-Jin Lee and Jun-Bom Park, Preparation of Celecoxib Tablet by Hot Melt Extrusion Technology and Application of Process Analysis Technology to Discriminate Solubilization Effect, Pharmaceutical Development and Technology, 2020, 25(5), 525-534

Bhupendra Raj Giri, Eon Soo Song, Jaewook Kwon, Ju-Hyun Lee, Jun-Bom Park and Dong Wuk Kim, Fabrication of Intragastric Floating, Controlled Release 3D Printed Theophylline Tablets Using Hot-Melt Extrusion and Fused Deposition Modeling, Pharmaceutics, 2020, 12, 77

Dayoung Kim, Chulhun Park, Nileshkumar M. Meghani, Thao T.D. Tran, Phuong H.L. Tran, Jun-Bom Park, Beom-Jin Lee, Utilization of a fattigation platform gelatin-oleic acid sodium salt conjugate as a novel solubilizing adjuvant for poorly water-soluble drugs via self-assembly and nanonization, International Journal of Pharmaceutics, 2020, 575, 118892

Sung-min Choi, Yong-Koo Jeon, Ju-Hyun Lee, Chin-Yang Kang, and Jun-Bom Park, Solubility Enhancement of Poorly Water-Soluble Drugs by Hot-Melt Extrusion Technology and Effects of Surfactant on Dissolution Test, J. Pharm. Soc. Korea, 2019, 63(6), 384-389

Shrawani Lamichhane, Jun-Bom Park, Dong Hwan Sohn and Sangkil Lee, Customized Novel Design of 3D Printed Pregabalin Tablets for Intra-Gastric Floating and Controlled Release Using Fused Deposition Modeling, Pharmaceutics, 2019, 11, 564-577

Chulhun Park, Nileshkumar M. Meghani, Yongkwan Shin, Euichaul Oh, Jun-Bom Park, Jing-Hao Cui, Qing-Ri Cao, Thao Truong-Dinh Tran, Phuong Ha-Lien Tran and Beom-Jin Lee, Investigation of Crystallization and Salt Formation of Poorly Water-Soluble Telmisartan for Enhanced Solubility, Pharmaceutics, 2019, 11, 102-117

Kyu-Yeol Nama, Sang Min Cho, Youn-Woong Choi, Chulhun Park, Nileshkumar M. Meghani, Jun-Bom Park, Beom-Jin Lee, Double controlled release of highly insoluble cilostazol using surfactant- driven pH dependent and pH-independent polymeric blends and in vivo bioavailability in beagle dogs, International Journal of Pharmaceutics, 2019, 558, 284-290

Changmin Kang, Ju-Hyun Lee, Dong-Wook Kim, Beom-Jin Lee, and Jun-Bom Park, Preparation of Sustained Release Tablet with Minimized Usage of Glyceryl Behenate Using Post-Heating Method, AAPS PharmSciTech, 2018, 19(7), 3067-3075

Seung Jin Ko, Ju-Hyun Lee, Chin-Yang Kang, Jun-Bom Park, Granulation development in batch-to-batch and continuous processes from a quality by design perspective, Journal of Drug Delivery Science and Technology, 2018, 46, 34-45

Jun-Bom Park, Chulhun Park, Zhong Zhu Piao, Hardik H. Amin, Nilesh M. Meghani, Phuong H.L. Tran, Thao T.D. Tran, Jing-Hao Cui, Qing-Ri Cao, Euichaul Oh, Beom-Jin Lee, pH-independent controlled release tablets containing nanonizing valsartan solid dispersions for less variable bioavailability in humans, Journal of Drug Delivery Science and Technology, 2018, 46, 365-377

Nilesh M. Meghani, Hardik H. Amin, Chulhun Park, Jun-Bom Park, Jing-Hao Cui, Qing-Ri Cao, Beom-Jin Lee, Design and evaluation of clickable gelatin-oleic nanoparticles using fattigation-platform for cancer therapy, International Journal of Pharmaceutics, 2018, 545, 101-112

Kyung-Ho Lee · Chulhun Park · Giwon Oh · Jun-Bom Park · Beom-Jin Lee, New blends of hydroxypropylmethylcellulose and Gelucire 44/14: physical property and controlled release of drugs with different solubility, Journal of Pharmaceutical Investigation, 2018, 48, 313-321

Namhyun Baek, Ga-Hui Oh, Chulhun Park, Thuy Thi Thanh Tran, Young Joon Park, Euichaul Oh, Hau Le, Thao T.D. Tran, Jun-Bom Park, Beom-Jin Lee, Reprecipitation of poorly water-soluble cilostazol crystals using adsorbing carriers for enhanced dissolution and physicochemical modification. Journal of Drug Delivery Science and Technology, 2018, 43, 477-486

Sung-min Choi, Chin-Yang Kang, Beom Jin Lee and Jun-Bom Park, In Vitro-In Vivo Correlation Using In Silico Modeling of Physiological Properties, Metabolites, and Intestinal Metabolism. Current Drug Metabolism, 2017, 18(11), 973-982

Sultan Alshehri, Roshan Tiwari, Bader Alsulays, Eman Ashour, Abdullah Alshetaili, Bjad Almutairy, Jun-Bom Park, Joseph Morott, Bhupinder Sandhu, Soumyajit Majumdar & Michael A. Repka, Investigation of the combined effect of MgO and PEG on the release profile of mefenamic acid prepared via hot-melt extrusion techniques. Pharmaceutical Development and Technology, 2017, 22(6), 740-753

Daoqi Luo, Joo Hee Kim, Chulhun Park, Euichaul Oh, Jun-Bom Park, Jing-Hao Cui, Qing-Ri Cao, Beom-Jin Lee, Design of fixed dose combination and physicochemical characterization of enteric-coated bilayer tablet with circadian rhythmic variations containing telmisartan and pravastatin sodium. International Journal of Pharmaceutics, 2017, 523, 343-356

Ilhwan Hwang, Chin-Yang Kang, Jun-Bom Park, Advances in hot-melt extrusion technology toward pharmaceutical objectives. Journal of Pharmaceutical Investigation, 2017, 47, 123-132

Jun-Bom Park, Dong-Wook Kim, Sung-Hoon Lee, Kwon-Yeon Weon, Development of a Process Analytical Technology(PAT) method using near-infrared spectroscopy system for evaluating an active coating process for a low-dose drug. Journal of Drug Delivery Science and Technology, 2017, 39, 8-15

Jun-Bom Park, Beom-Jin Lee, Chin-Yang Kang, Roshan V. Tiwari, Michael A. Repka, Process analytical quality control of tailored drug release formulation prepared via hot-melt extrusion technology. Journal of Drug Delivery Science and Technology, 2017, 38, 51-58

Bader B. Alsulays, Vijay Kulkarni, Sultan M. Alshehri, Bjad K. Almutairy, Eman A. Ashour, Joseph T. Morott, Abdullah S. Alshetaili, Jun-Bom Park, Roshan V. Tiwari & Michael A. Repka, Preparation and evaluation of enteric coated tablets of hot melt extruded lansoprazole. Drug Development and Industrial Pharmacy, 2017, 43(5), 789-796

Abdullah S. Alshetaili, Bjad K. Almutairy, Roshan V. Tiwari, Joseph T. Morott, Sultan M. Alshehri, Xin Feng, Bader B. Alsulays, Jun-Bom Park, Feng Zhang and Michael A Repka, Preparation and Evaluation of Hot-Melt Extruded Patient-Centric Ketoprofen Mini-tablets. Current Drug Delivery, 2016, 13(5), 730-741

Eman A. Ashour, Vijay Kulkarni, Bjad Almutairy, Jun-Bom Park, Sejal Shah, Soumyajit Majumdar, Michael A. Repka, Influence of Pressurized Carbon Dioxide on Ketoprofen-Incorporated Hot-Melt Extruded Low Molecular Weight Hydroxypropylcellulose. Drug Development and Industrial Pharmacy, 2016, 42 (1), 123-130



도서 ( Books )
이범진, 손동환, 한효경, 오경택, 박준범, 김성원, 최연웅, 장희철, 김병조, 박상욱, 글로벌 개량신약 연구개발과 질환별 사업화전략. 신일서적. 2020.

이범진, 전인구, 한효경, 박준범, 임지성, 염류의약품 물성과 선택 및 응용. 신일북스 (역자). 2013.
Jun-Bom Park and Beom-jin Lee, Emerging oral controlled-release technology for optimal therapy. Future Science, 2013, Nov. 40-53.



특허 ( Patents )
박준범, 오혜성, 아세트아미노펜 및 이부프로펜을 포함하는 3D 프린터용 필라멘트, 이를 이용한 이중방출 제형 및 제조방법, 10-2024-0035289 (출원번호)

박준범, 이주현, 아리피프라졸을 포함하는 필라멘트와, 3D 프린트된구강붕해 필름 및 이의 제조방법, 10-2023-0096550 (Korean Patent)

Sampada Bhaskar Upadhye, Michael Andrew Repka, Jun-Bom Park, Roshan Vijay Tiwari, Hemlata Gunga Patil, Joseph Thomas Morott, Wenli Lu, Twin-screw dry granulation for producing solid formulations. US 10,786,459 B2

Hemlata Patil, Vijay Kulkarni, Jun-Bom Park, Soumyajit Majumdar, Michael A. Repka, Systems and Methods for Preparing Lipid Nanoparticles. WO 2015/148483 A1

박준범, 최성민, 생리학적 체내 동태 연구 모델링을 이용한 약제학적 조성물의 제조 방법, 10-2114550 (Korean Patent)

박준범, 강창민, 친수성 약물을 포함하는 서방성 제제의 제조 방법, 2018, 제 10-1881749 호. (Korean Patent)

박준범, 강진양, 반복 고온용융 압출 성형된 약제학적 조성물의 제조 방법 및 이에 의해 제조된 약제학적 조성물, 2017, 제 10-1801476 호. (Korean Patent)

박준범, 이범진, 고온용융 압출을 이용한 저함량 약제학적 조성물의 제조방법, 2013, 제 10-1390946 호. (Korean Patent)

경력

2001.2~2004.4 초당약품 ㈜, 연구소 근무; 선임연구원
2004.5~2008.2 ㈜ 한독약품, 연구소 근무; Project Manager
2013.4~2015.02 University of Mississippi; Post-Doc Researcher
2015.3~2021.2 삼육대학교 약학대학 약학과 조교수
2021.3~ 삼육대학교 약학대학 약학과 부교수
2022.08~2023.07 School of Pharmacy, Lomalinda University 교환교수

학회 (Society)
1) 대한약학회 정회원
2) 한국약제학회 정회원

CERTIFICATION
License for Pharmacist in Korea, Feb. 1999

학력

1988. 2. 삼육대학교 약학과, 약학사
2000. 2. 숙명여자대학교 대학원 임상약학석사
2006. 9. 삼육대학교 대학원 약학박사

논문

1. An, J., et al., Modulation of Pro-inflammatory and Anti-inflammatory Cytokines in the Fat by an Aloe Gel-based Formula, QDMC, Is Correlated with Altered Gut Microbiota. Immune Netw, 2021. 21(2): p. e15.

2. Choi, D., et al., Amelioration of Benign Prostatic Hyperplasia by Costunolide and Dehydrocostus Lactone in Wistar Rats. World J Mens Health, 2021. 39(2): p. 315-323.

3. Lee, H., et al., A Novel Bacterium, Butyricimonas virosa, Preventing HFD-Induced Diabetes and Metabolic Disorders in Mice via GLP-1 Receptor. Front Microbiol, 2022. 13: p. 858192.

4. 송영천, 항암치료 병용요법에 있어서 Exosome 기반 약물전달시스템의 적용. 병원약사회지, 2023. 40(2): p. 222-231.

5. An, J., et al., Alteration of Gut Microbes in Benign Prostatic Hyperplasia Model and Finasteride Treatment Model. Int J Mol Sci, 2023. 24(6).

6. Kim, S., et al., Unripe Rubus occidentalis, Ellagic Acid, and Urolithin A Attenuate Inflammatory Responses in IL-1β-Stimulated A549 Cells and PMA-Stimulated Differentiated HL-60 Cells. Nutrients, 2023. 15(15).

7. Lee, H., et al., Chemokine CCL6 Plays Key Role in the Inhibitory Effect of Vitamin A on Norovirus Infection. J Microbiol, 2023. 61(5): p. 579-587.

8. Padasas, B.T., et al., COVID-19 Therapeutics: An Update on Effective Treatments Against Infection With SARS-CoV-2 Variants. Immune Netw, 2023. 23(2): p. e13.

9. Seo, C.H., et al., Evaluation of Comprehensive Effects of Methanol Extracts of Coptidis rhizoma against Several Oral Pathogenic Bacteria. Korean Journal of Pharmacognosy, 2023. 54(1): p. 27-37.

10. Kim, J., et al., Hair Growth Promoting Effects of Solubilized Sturgeon Oil and Its Correlation with the Gut Microbiome. Pharmaceuticals (Basel), 2024. 17(9).

11. Shin, Y., et al., Efficacy of Laurus nobilis L. for Tight Junction Protein Imbalance in Leaky Gut Syndrome. Nutrients, 2024. 16(9).

경력

1993. 3. – 2013. 1. 서울아산병원 약제팀
2007. 1. – 2012. 12. 서울아산병원 약제팀장
2013. 3. – 현재. 삼육대학교 약학대학 부교수

[수상]
2006. 식품의약품안전청장상
2010. 복지부장관상

학력

03/2008-02/2012 B.S., College of Pharmacy, Sahmyook University, Korea
03/2012-02/2016 M.S., College of Pharmacy, Sahmyook University, Korea (Pharmacognosy)
03/2016-08/2020 Ph.D., College of Pharmacy, Seoul National University, Korea (Pharmacognosy/Natural Products Science)

논문

1. Myeong JH‡, Lee MH‡, Lee BW‡, Kim JH, Nam YJ, Choi YS, Kim JM, Jeon SY, Shim HW, Jung DR, Shin YJ, Jeong MS, Oh BM, Jung JH, Kim CS, Han HS, Shin JH, Lee YH, Park NJY, Chong GO, Jeong YT. Microbial metabolites control self-renewal and precancerous progression of human cervical stem cells. Nat. Commun. 2025, 16, 2327. ‡co-first authors
2. Park EJ‡, Lee BW‡, Ryu B, Cho HM, Kim SK, Yoo SS, Kim E, Oh WK. Antiviral activity of CAVAC-1901, a combination of three standardized medicinal plants against highly pathogenic influenza A virus in chickens. Poult. Sci. 2023, 102, 102315. ‡co-first authors
3. Kim EH‡, Lee BW‡, Ryu B‡, Cho HM, Kim SM, Jang SG, Casel MAB, Rollen R, Yoo JS, Poo H, Oh WK, Choi YK. Inhibition of a broad range of SARS-CoV-2 varients by antiviral phytochemicals in hACE2 mice. Antiviral Res. 2022, 204, 105371. ‡co-first authors
4. Lee BW, Ha TKQ, Park EJ, Cho HM, Ryu B, Doan TP, Lee HJ, Oh WK. Melicopteline A-E: Unusual cyclopeptide alkaloids with antiviral activity against influenza A virus from Melicope pteleifolia. J. Org. Chem. 2020, 86, 1437-1447.
5. Lee BW, Ha TKQ, Cho HM, An JP, Kim SK, Kim CS, Kim E, Oh WK. Antiviral activities of furanocoumarins isolated from Angelica dahurica against influenza A virus H1N1 and H9N2. J. Ethonopharmacol. 2020, 259, 112945.
6. Ha TKQ‡, Lee BW‡, Nguyen NH, Cho HM, Venkatesan T, Doan TP, Kim E, Oh WK. Antiviral activities of compounds isolated from Pinus densiflora (pine tree) against the influenza A virus. Biomolecules 2020, 10, 711. ‡co-first authors
7. Kim AR‡, Kim SW‡, Lee BW‡, Kim KH, Kim WH, Seok H, Lee JH, Um J, Yim SH, Ahn Y, Jin SW, Jung DW, Oh WK, Williams DR. Screening ginseng saponins in progenitor cells identifies 20(R)-ginsenoside Rh2 as an enhancer of sckeletal and cardiac muscle regeneration. Sci. Rep. 2020,10, 4967. ‡co-first authors
8. Lee BW, Park JG, Ha TKQ, Pham HTT, An JP, Noh JR, Lee CH, Oh WK. Constituents of the edible leaves of Melicope pteleifolia with potential analgesic activity. J. Nat. Prod. 2019, 82, 2201-2210.
9. Lee BW, Ha TKQ, Pham HTT, Hoang QH, Tran VO, Oh WK. Hydroxyoleoside-type seco-iridoids from Symplocos cochinchinensis and their insulin mimetic acitivity. Sci. Rep. 2019, 9, 2270.

Patents
1. Patent registration (Republic of Korea): 1019879710000. Composition for preventing or treating arthritis, comprising aromatic ketone compound, Melicope pteleifolia extract, or fraction thereof containing the same.
2. Patent registration (Republic of Korea): 1018273740000. Composition for treating, improving or preventing aging and aging-related diseases.
3. Patent registration (Republic of Korea): 1017931450000. A composition for preventing or treating metabolic disease comprising Sicyos angulatus extract or fraction thereof.
4. Patent application (Republic of Korea): 1020220173536. Producing method of cervix organoid and uses thereof.
5. Patent application (Republic of Korea): 1020210019475. Antiviral agent with inhibitory activitity on SARS-coronavirus-2 by phloroglucinol compounds from Dryopteris crassirhiza and compositions for treatment and prevention of COVID-19 containing the same as an active ingredient.
6. Patent application (Republic of Korea): 1020210019462. Composition for preventing or treating severe acute respiratory syndrome- corona virus infection comprising Chlorella sp. extract or pheophytinized fraction or pyphyrins or carotenones isolated therefrom as active ingredients.
7. Patent application (Republic of Korea): 1020210004704. Composition for preventing or treating avian influenza virus infection comprising Angelica dahurica, Curcuma longa and Resina Pini extract.
8. Patent application (Republic of Korea): 1020210007185. Composition for preventing or treating swine influenza virus disease comprising Resina Pini extract or diterpenoids isolated therefrom as active ingredients.
9. Patent application (Republic of Korea): 1020200164396. Composition for preventing or treating influenza virus disease comprising Angelica dahurica, Curcuma longa and Resina Pini extract.
10. Patent application (Republic of Korea): 1020200051446. Composition for preventing or treating swine influenza virus disease comprising Curcuma longa extract or sesquiterpenoids isolated therefrom as active ingredients.
11. Patent application (Republic of Korea): 1020190111752. A composition for prevention or treatment of diabetic related disease comprising extract of Symplocos spp. or compound isolated from thereof.

경력

03/2012-07/2013 Pharmacist, Seoul Medical Center, Korea
09/2015-02/2016 Assistant Researcher, College of Pharmacy, Seoul National University, Korea
09/2020-10/2021 Postdoctoral Fellow, College of Pharmacy, Seoul National University, Korea (Pharmacognosy/Natural Products Science)
11/2021-02/2024 Postdoctoral Fellow, Department of New Biology, DGIST, Korea (Stem Cell Biology/Organoid)
03/2024-present Assistant Professor, College of Pharmacy, Sahmyook University, Korea (Pharmacognosy)

Awards and Honors
1. Best poster award: 2023 Annual Meeting of the Organoid Society (2023.10.26).
2. Poster competition winner: The 51th Annual Meeting and Symposium of the Korean Society of Pharmacognosy (2020.12.02).

Grant
1. Grant: Basic Science Research (NRF, 2022)
NRF grant number: 2022R1I1A1A01071095
Project title: Identification of the human ectocervical stem cell using the organoid culture system and the effect of human papillomavirus infection on cervical stem cells. Project Start/End: 2022.06.01~2025.05.31 (₩ 70,000,000/year)

학력

1986. 2 삼육대학교 약학과, 약학사
1988. 2 서울대학교 대학원 약학과, 약학석사(약품미생물학 전공)
1995. 2 서울대학교 대학원 약학과, 약학박사(약품미생물학 전공)

논문

1. So Won Kang, Chae Hyeon Seo, Sungsook Choi. 2024. Anti-periodontitic Effects of Weisiella cibaria SPM402 and Lactobacillus paracasei SPM412 Isolated from Korean Traditional Foods. J. Food Hyg. Saf. 39: 343-352

2. Chae Hyeon Seo, So Won Kang, Sungsook Choi. 2024. Inhibition Effects of Weisiella cibaria SPM402 and Lactobacillus paracasei SPM412 against Gingipains as a Major Virulence Factor for Porphyromonas gingivalis. J. Food Hyg. Saf. 38: 544-550

3. Chae Hyeon Seo, YoungCheon Song, Dongsool Yim, Sungsook Choi. 2023. Evaluation of Comprehensive Effects of Methanol Extracts of Coptidis rhizoma against Several Oral Pathogenic Bacteria. Kor. J. Pharmacogn. 54: 27-37

4. Eui Jin Kim, Tae Seo Sohn, Hyun Ho Choi, Hui Yeong Oh, Sang Ho Park, Young-Chang Cho, Jin-Oh Jung, Jeong Sun Sohn, Hae Kyung Lee, Sung Sook Choi, and Hiun Suk Chae. 2023. High levle of Akkermansia muciniphilia growth associated with spring water ingestion prevents obesity and hyperglycemia in a high-fat diet induced mouse model. Nat. Prod. Commun. 17:1-9

5. Hui Yeong Oh, Hyun Ho Choi, Eui Jin Kim, Ji Hye Choi, Sung Sook Choi, Hae Kyung Lee, Hyung‑Keun Kim, Sang Woo Kim, Won Sang H. Park, Hiun Suk Chae. 2022. In vitro and in vivo phototoxicity on gastric mucosa induced by methylene blue. Saudi. J. Gastroenterol. 29:53-58. doi: 10.4103/sjg.sjg_315_22.

6. JungHyeok Lee, Dongsool Yim, SungSook Choi. 2021. Antibacterial activity and Anti-inflammatory effect of Methanol Extracts of Saliva miltiorrhiza against Oral Pathogenic Bacteria. Kor. J. Pharmacogn. 52: 41-48

7. SungSook Choi, Hui Yeong Oh, Eui Jin Kim, Hae Kyung Lee, Hyung Keun Kim, Hyun Ho Choi, Sang Woo Kim, Hiun Suk Chae. 2020. In Vitro Bactericidal Effects of Photodynamic Therapy Combined with Four Tetracyclines against Clostridioides difficile KCTC5009 in Planktonic Cultures. Pathogens, 9, 279; doi:10.3390/pathogens9040279

8. Min Kyoung Choi, SungSook Choi. 2020. In vitro and in vivo anti-clostridial activity of newly isolated Pediococcus acidilactici SPM138 against Clostridium difficile. Anaerobe. 2020 Feb;61:102146. doi: 10.1016/j.anaerobe.2019.102146. Epub 2019 Dec 27.

9. Eui Jin Kim, Ji Hye Choi, Hyun Jung Yang, SungSook Choi, Hae Kyung Lee, Young-Chang Cho, Hyung Keun Kim, Sang Woo Kim, Hiun Suk Chae. 2019. Comparison of high and low molecular weight chitosan as in-vitro boosting agent for photodynamic therapy against Helicobacter pylori using methylene blue and endoscopic light. Photodiagnosis and Photodynamic Therapy 26: 111–115

10. SungSook Choi, HaeKyung Lee, JinWoo Kim, JiHan Yu, HyunHo Choi, HyungKeun Kim, SangWoo Kim, Hiun Suk Chae. 2019. DUKKU and BAEKAM springwater inhibit the urease activity of Helicobacter pylori. Afr. J. Complemen.t Altern. Med. 16: 34-40.

11. Jung Hwan Yoon, Olga Kim, Jung Woo Eun, Sung Sook Choi, Hassan Ashktorab, Duane T. Smoot, Suk Woo Nam, Won Sang Park. 2018. Multiple genetic mutations caused by NKX6.3 depletion contribute togastric tumorigenesis. Scientific reports 8:17609 | DOI:10.1038/s41598-018-35733-5

12. Choi Min Kyeong, Dongsool Yim, SungSook Choi. 2018. Anti-bacterial and Anti-inflammatory Effects of Angelica dahurica Extracts in Helicobacter pylori-infected Human Gastric Epithelial AGS Cells. Kor. J. Pharmacogn. 49(3), 255-261.

경력

1995.2-1997.2. 서울대학교 종합약학연구소 박사 후 연구원
1997.2-1999.2 삼육대학교 생명과학연구소 연구원
1999.3-2000.8 삼육의명대학 전임강사
2000.8-2005.8 삼육의명대학 조교수
2005.8-2006.2 삼육의명대학 부교수
2006.3-2011.8 삼육대학교 약학대학 부교수
2006.9-2007.8 Washington University in St. Louis, School of Medicine, 연구교수
2011.9-현재 삼육대학교 약학대학 교수
2016-2-2020.1 삼육대학교 약학대학 학장